Recombinant Bovine Single-strand selective monofunctional uracil DNA glycosylase (SMUG1)

中文名稱：

牛SMUG1重組蛋白
貨號：

CSB-YP710546BO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

牛SMUG1重組蛋白
貨號：

CSB-EP710546BO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

牛SMUG1重組蛋白
貨號：

CSB-EP710546BO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

牛SMUG1重組蛋白
貨號：

CSB-BP710546BO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

牛SMUG1重組蛋白
貨號：

CSB-MP710546BO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SMUG1
Uniprot No.：

Q59I47
別名：

SMUG1; Single-strand selective monofunctional uracil DNA glycosylase; EC 3.2.2.-
種屬：

Bos taurus (Bovine)
蛋白長度：

full length protein
表達區域：

1-272
氨基酸序列

MAVPQPFPSG PHLQPAGALM EPQPSPRSLA EGFLQEELRL NDELRQLQFS ELVGIVYNPV EYAWEPHRSY VTRYCQGPKQ VLFLGMNPGP FGMAQTGVPF GEVSVVRDWL GLGGPVRTPP QEHPKRPVLG LECPQSEVSG ARFWGFFRNL CGQPEVFFRH CFVHNLCPLL LLAPSGRNIT PAELPAKQRE QLLGVCDAAL CRQVQLLGVR LVVGVGRVAE QRARRALASL MPEVQVEGLL HPSPRSPQAN KGWEAVAKER LNELGLLPLL TS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.
亞細胞定位：

Nucleus.
蛋白家族：

Uracil-DNA glycosylase (UDG) superfamily, SMUG1 family
數據庫鏈接：

KEGG: bta:539771

STRING: 9913.ENSBTAP00000029297

UniGene: Bt.64531