Recombinant Bovine C-X-C chemokine receptor type 2 (CXCR2), partial

中文名稱：

Recombinant Bovine C-X-C chemokine receptor type 2(CXCR2),partial
貨號：

CSB-YP632950BO1
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Bovine C-X-C chemokine receptor type 2(CXCR2),partial
貨號：

CSB-EP632950BO1
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Bovine C-X-C chemokine receptor type 2(CXCR2),partial
貨號：

CSB-EP632950BO1-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Bovine C-X-C chemokine receptor type 2(CXCR2),partial
貨號：

CSB-BP632950BO1
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Bovine C-X-C chemokine receptor type 2(CXCR2),partial
貨號：

CSB-MP632950BO1
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

CXCR2
Uniprot No.：

Q28003
別名：

CXCR2; IL8RB; C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; High affinity interleukin-8 receptor B; IL-8R B; CD antigen CD182
種屬：

Bos taurus (Bovine)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
基因功能參考文獻：
1. no statistically significant association of the SNP CXCR1+777 or CXCR1-1768 with SCS was found PMID: 19620685
2. Data describe the expression of IL-8, IL-1beta and their respective receptors, CXCR1 and IL-1R1 in bovine theca cells, and suggest that VEGF is associated with the IL system in theca cells in ovary. PMID: 20156197
3. The aim of this study was to demonstrate the presence of the two SNPs in the CXCR1 gene of Japanese Black cattle and examine the association between the SNPs and clinical diseases including intestinal and respiratory diseases in calves. PMID: 20697186
4. Association between interleukin-8 receptor-alpha (CXCR1) polymorphism and disease incidence, production, reproduction, and survival in Holstein cows. PMID: 21426999
5. The situation of CXCR1 polymorphisms in Chinese Holstein cattle and determine the relationship between the CXCR1 SNPs and mastitis resistance. PMID: 21774621
6. highly polymorphic PMID: 22056270
7. The results suggests the possible role of CXCR1 gene SNPs in the host response against mastitis. PMID: 23979897
8. CXCR1 polymorphisms influence viability and concentration of milk polymorphonuclear neutrophilic leukocytes. PMID: 24934516
9. The results demonstrate that CXCR1 polymorphism can influence somatic cell count and milk neutrophil viability following experimental mastitis. PMID: 25933826
10. In the present study no association could be detected between superoxide production by isolated bovine neutrophils during early lactation and CXCR1 gene polymorphism. IL-8 showed to possess inhibitory effects on ROS generation in bovine neutrophils. PMID: 25944115
11. Polymorphisms in CXCR1 are significantly associated with bovine mastitis PMID: 26126595
12. (PCR) was used to detect the methylation status of CXCR1 CpG island, and quantitative fluorescence PCR was used to detect CXCR1 expression in bovine mammary tissue PMID: 26505411
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亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

G-protein coupled receptor 1 family
數據庫鏈接：

KEGG: bta:281863

STRING: 9913.ENSBTAP00000056463

UniGene: Bt.111573