Recombinant Arabidopsis thaliana WD-40 repeat-containing protein MSI4 (MSI4), partial

中文名稱：

擬南芥MSI4重組蛋白
貨號：

CSB-YP517778DOA
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

擬南芥MSI4重組蛋白
貨號：

CSB-EP517778DOA
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

擬南芥MSI4重組蛋白
貨號：

CSB-EP517778DOA-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

擬南芥MSI4重組蛋白
貨號：

CSB-BP517778DOA
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

擬南芥MSI4重組蛋白
貨號：

CSB-MP517778DOA
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

MSI4
Uniprot No.：

O22607
別名：

MSI4; ACG1; FVE; At2g19520; F3P11.12; WD-40 repeat-containing protein MSI4; Altered cold-responsive gene 1 protein
種屬：

Arabidopsis thaliana (Mouse-ear cress)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of the flowering autonomous pathway which positively regulates flowering by promoting transcriptional repression of the flowering repressor FLC. May promote histone deacetylation at the FLC locus leading to the formation of repressive chromatin structures. Forms a histone deacetylase complex with HDA5, HDA6 and FLD that represses FLC gene expression to control flowering time. Also negatively regulates cold-responsive genes. Acts together with PDP1 and MSI5 to regulate the function of the PRC2 complex on FLC.
基因功能參考文獻：
1. We also demonstrate that PTM, a PHD transcription factor involved in chloroplast retrograde signaling, perceives such a signal and mediates transcriptional repression of FLC through recruitment of FVE, a component of the histone deacetylase complex. PMID: 27601637
2. Data propose these novel ATMSI4-associated proteins help form nucleoprotein complexes that determine pleiotropic functional properties of AtMSI4/FVE/ACG1 involving plant development PMID: 25600937
3. FVE is essential for the HOS1-mediated activation of FLC transcription. PMID: 24220632
4. Two phospho-beta-galactosidase, LacG1 and LacG2, are the primary enzymes for lactose utilization in Lb. gasseri. PMID: 22449746
5. we report that two Arabidopsis homologs of the human histone-binding proteins Retinoblastoma-Associated Protein 46/48 (RbAp46/48), known as MSI4 (or FVE) and MSI5, function in partial redundancy in chromatin silencing of various loci targeted by siRNAs PMID: 22102827
6. FVE, an Arabidopsis homologue of the retinoblastoma-associated protein that regulates flowering time and cold response, binds to chromatin as a large multiprotein complex. PMID: 21710206
7. These results suggest that there may be a conserved function between OsFVE and FVE in the control of flowering time. PMID: 18612241
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亞細胞定位：

Nucleus.
蛋白家族：

WD repeat RBAP46/RBAP48/MSI1 family
組織特異性：

Expressed in rosette leaves, cauline leaves, main stems and developing fruits. Expressed at higher levels in roots and flowers.
數據庫鏈接：

KEGG: ath:AT2G19520

STRING: 3702.AT2G19520.1

UniGene: At.20032