AGPS Recombinant Monoclonal Antibody
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中文名稱：AGPS Recombinant Monoclonal Antibody
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貨號：CSB-RA196051A0HU
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規格：￥1320
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圖片：
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Flow cytometric analysis of Alkylglycerone phosphate synthase expression in HeLa cells using Alkylglycerone phosphate synthase antibody. Green, isotype control; red, Alkylglycerone phosphate synthase. -
Immunocytochemical staining of Hela cells with Alkylglycerone phosphate synthase antibody. Nuclei were stained blue with DAPI; Alkylglycerone phosphate synthase was stained magenta with Alexa Fluor? 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Low. Scale bar, 20 μm. -
Western blotting analysis using alkylglycerone phosphate synthase antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with alkylglycerone phosphate synthase antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：AGPS; Alkylglycerone Phosphate Synthase; ALDHPSY; ADHAPS; ADAP-S; ADAS; ADPS; Alkyldihydroxyacetonephosphate Synthase, Peroxisomal; Aging-Associated Gene 5 Protein; Alkyl-DHAP Synthase; EC 2.5.1.26; Alkylglycerone-Phosphate Synthase; Aging-Associated Protein 5; RCDP3
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反應種屬：Human, Rat
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免疫原：Recombinant Human AGPS protein
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Monoclonal
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抗體亞型：Rabbit IgG
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純化方式：Affinity-chromatography
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克隆號：22B9
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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產品提供形式：Liquid
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應用范圍：ELISA, WB, FC, ICC
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 FC 1:200-1:2000 ICC 1:100-1:1000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Catalyzes the exchange of the acyl chain in acyl-dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl-dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis.
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基因功能參考文獻：
- we optimized the BITC construction targeting alkylglycerone phosphate synthase (AGPS) by computer-aided design, and the derivants also showed anti-tumor potential in vitro. PMID: 25542233
- AGPS overexpression could be a causation of chemotherapy agent resistance of cancer cells. AGPS silencing could lead to drug uptake and cell cycle arrest and apoptotic cell death. PMID: 24815474
- Results demonstrated that AGPS negatively regulated the invasion potential of glioma and hepatic carcinoma cells by modulating the expression of relevant genes and activity of the MAPK pathway. PMID: 24841318
- AGPS, in addition to maintaining ether lipids, also controls cellular utilization of fatty acids, favoring the generation of signaling lipids necessary for promoting the aggressive features of cancer. PMID: 23980144
- Novel mutations in AGPS (alkylglycerone-phosphate synthase) cause rhizomelic chondrodysplasia punctata (RCDP) type 3. PMID: 21990100
- Defect of ADAPS expression was also assessed by immunoblot PMID: 18571506
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相關疾病：Rhizomelic chondrodysplasia punctata 3 (RCDP3)
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亞細胞定位：Peroxisome membrane. Peroxisome.
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蛋白家族：FAD-binding oxidoreductase/transferase type 4 family
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數據庫鏈接：
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