Recombinant Rat Complement C1q subcomponent subunit B (C1qb)
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中文名稱：Recombinant Rat Complement C1q subcomponent subunit B(C1qb)
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貨號：003638RA
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規格：
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：C1qb; Complement C1q subcomponent subunit B
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免疫原種屬：Rattus norvegicus (Rat)
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
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應用說明：Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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儲存條件：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
靶點詳情
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功能：C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
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基因功能參考文獻：
- Data suggest that complement C1q expression may play a principal role in hepatic ischemia-reperfusion (I/R) injury, particularly at the early stage of perfusion. PMID: 24939307
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亞細胞定位：Secreted.
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組織特異性：Highest levels in spleen, lung and brain. Weaker expression in kidney and liver. In the spleen, localized mainly to the red pulp, in cells mainly of monocyte-macrophage lineage. In white pulp, localized in specific dendritic cells such as those from the p
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