bamB Antibody

^{Rare Species}

說明書

中文名稱：

bamB兔多克隆抗體
貨號：

CSB-PA300609XA11ENV
規格：

￥440
圖片：
Western Blot
Positive WB detected in: recombinant protein
All lanes: bamB Antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 31 kDa
Observed band size: 31 kDa
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

Uniprot No.：

P77774
基因名：

bamB
別名：

Outer membrane protein assembly factor BamB, bamB, yfgL
反應種屬：

E.coli
免疫原：

Recombinant E.coli bamB protein (125-386aa)
免疫原種屬：

Escherichia coli(strain K12)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Affinity-chromatography
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Part of the outer membrane protein assembly complex (Bam), which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Nonessential member of the complex, which may orient the flexible periplasmic domain of BamA for interaction with other Bam components, chaperones and nascent outer membrane proteins. Efficient substrate folding and insertion into the outer membrane requires all 5 subunits. A lateral gate may open between the first and last strands of the BamA beta-barrel that allows substrate to insert into the outer membrane; comparison of the structures of complete and nearly complete Bam complexes show there is considerable movement of all 5 proteins.
基因功能參考文獻：
1. The crystal structure shows that BamB has an eight-bladed beta-propeller structure, with four beta-strands making up each blade. PMID: 21168416
2. BamB could simultaneously bind to BamA and prefolded beta-barrel proteins, thereby enhancing the folding and membrane insertion capability of the Bam complex. PMID: 21236263
3. A yfgL- negative isogenic mutant showed a marked decrease both in its ability to invade Intestine-407 cells and in the amount of the outer membrane proteins OmpA and OmpC. PMID: 15774871
4. YfgL is part of a multiprotein complex involved in the assembly of outer membrane beta barrel proteins PMID: 15851036
5. The data presented here suggest that the yfgL effect on outer membrane proteins also stems from a defective assembly apparatus, leading to aberrant outer membrane protein assembly, except for TolC PMID: 17015657
6. The periplasmic phosphoquinolipoprotein kinase YfgL plays an important role in radiation-induced DNA strand break repair and homologous recombination in E. coli. PMID: 17630970
7. Report show that the region of YfgL encompassing L173, L175, and R176 makes direct contact with YaeT and that altering residues D227 and D229 in another region of YfgL from E221 to D229 resulted in defective YaeT bindings. PMID: 18165306
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亞細胞定位：

Cell outer membrane; Lipid-anchor.
蛋白家族：

BamB family
數據庫鏈接：

KEGG: ecj:JW2496

STRING: 316385.ECDH10B_2678

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