ZNF410 Antibody

說明書

產品詳情

Uniprot No.：

Q86VK4
基因名：

ZNF410
別名：

Another partner for ARF 1 antibody; APA 1 antibody; APA1 antibody; Clones 23667 and 23775 zinc finger protein antibody; D12Ertd748e antibody; Zfp410 antibody; Zinc finger protein 410 antibody; Zinc finger protein APA 1 antibody; Zinc finger protein APA-1 antibody; ZN410_HUMAN antibody; Znf410 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human ZNF410
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription factor that binds to the sequence motif 5'-CATCCCATAATA-3' in regulatory elements and modulates transcription of target genes. Indirectly represses transcription of HBG1 and HBG2, hemoglobin subunits gamma-1 and gamma-2, in erythroid cells, via direct transcriptional activation of the chromodomain protein CHD4, a component of the NuRD complex. Activates transcription of matrix-remodeling genes such as MMP1 during fibroblast senescence. Activates transcription of the gap junction gene GJC1, perhaps in response to increasing glucose.
基因功能參考文獻：
1. No association was found between Apa1 genotypes and osteoporosis PMID: 26290023
2. APA1 has a role in inducing extracellular matrix remodeling genes PMID: 12370286
3. VDR polymorphism genotypes and haplotypes did not directly alter recurrence risk, but the reduction in risk associated with high dairy product intake was confined to individuals with ApaI aA/AA genotype. PMID: 18470879
亞細胞定位：

Nucleus.
組織特異性：

Widely expressed.
數據庫鏈接：

HGNC: 20144

KEGG: hsa:57862

STRING: 9606.ENSP00000407130

UniGene: Hs.270869

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