SSC1 Antibody

^{Rare Species}

說明書

中文名稱：

SSC1兔多克隆抗體
貨號：

CSB-PA206965XA01SVG
規格：

￥440
圖片：
Western Blot
Positive WB detected in Recombinant protein
All lanes: SSC1 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 35.4 kDa
Observed band size: 40 kDa
其他：

產品詳情
產品評價
靶點詳情

產品詳情

Uniprot No.：

P0CS90
基因名：

SSC1
別名：

Heat shock protein SSC1, mitochondrial (Endonuclease SceI 75 kDa subunit) (Endo.SceI 75 kDa subunit) (mtHSP70) SSC1 ENS1 YJR045C J1639
反應種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
免疫原：

Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) SSC1 protein (363-654aa)
免疫原種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
標記方式：

Non-conjugated
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Protein G
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Constitutes the ATP-driven core of the motor and binds the precursor preprotein. Required for the import of the processed frataxin homolog YFH1 into the mitochondrion.
基因功能參考文獻：
1. Amino acid substitution within SSC1 reveals structural elements within mtHsp70s that are required for allosteric modulation of the chaperone cycle. PMID: 24829379
2. Results show that mtHsp70-Cox4 complex likely serves as a novel delivery system to channel Cox4 into the assembly line when needed. PMID: 23864706
3. The intrinsic dynamics of the substrate-binding domain of Ssc1 was observed to be uncoupled from the dynamic interactions between substrate- and nucleotide-binding domains. PMID: 23624933
4. the critical amino acid sequence of Ssc1 and Ssc3 that can "make or break" mtHsp70 chaperone function. PMID: 21474445
5. interactions between Tim44 and mtHsp70, controlled by polypeptide binding, are required for efficient translocation across the mitochondrial inner membrane PMID: 15489862
6. The N-terminal 167-amino-acid segment of mature Tim44 is sufficient for both interaction with mtHsp70 and destabilization of a Tim44-mtHsp70 complex caused by client protein binding. PMID: 18426906
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亞細胞定位：

Mitochondrion matrix.
蛋白家族：

Heat shock protein 70 family
數據庫鏈接：

KEGG: sce:YJR045C

STRING: 4932.YJR045C

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