SIRPG Antibody
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中文名稱：SIRPG兔多克隆抗體
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貨號：CSB-PA021338GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：
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別名：gen like family member B antibody; bA77C3.1 antibody; CD172 antigen-like family member B antibody; CD172g antibody; CD172g antigen antibody; FLJ42230 antibody; RP11-77C3.2 antibody; Signal regulatory protein beta 2 antibody; Signal regulatory protein gamma antibody; Signal-regulatory protein beta-2 antibody; Signal-regulatory protein gamma antibody; SIRP B2 antibody; SIRP beta 2 antibody; SIRP gamma antibody; SIRP-b2 antibody; SIRP-beta-2 antibody; SIRP-gamma antibody; SIRPB2 antibody; SIRPG antibody; SIRPG_HUMAN antibody; SIRPgamma antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Human SIRPG
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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靶點詳情
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功能：Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation.
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基因功能參考文獻：
- SIRPgamma in complex with FabOX117 forms a dimer in the crystal. Binding to the Fab fixes the position of domain 1 relative to domains 2/3 exposing a surface which favours formation of a homotypic dimer. PMID: 23826770
- The independent non-obstructive azoospermia risk alleles are driven by variants in the protein-coding sequence of the two genes, SIRPA and SIRPG. PMID: 24162948
- a novel member of the signal regulatory protein (SIRP) family- with unique characteristics from both alpha and beta genes- termed SIRPgamma PMID: 15294972
- CD47 is enriched at endothelial junctions, and its interaction with SIRPgamma is required for human T-cell transendothelial migration PMID: 18524990
- tumor necrosis factor receptor superfamily, member 14 (TNFRSF14) and signal regulatory protein, gamma (SIRPG) appear to contribute to gender difference in incidence of systemic lupus erythematosus. PMID: 19473566
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亞細胞定位：Membrane; Single-pass type I membrane protein.
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組織特異性：Detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. Mainly present in the
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數據庫鏈接：
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