SCFD1 Antibody

說明書

產品詳情

Uniprot No.：

Q8WVM8
基因名：

SCFD1
別名：

C14orf163 antibody; Chromosome 14 open reading frame 163 antibody; RA410 antibody; Scfd1 antibody; SCFD1_HUMAN antibody; Sec1 family domain containing 1 antibody; Sec1 family domain-containing protein 1 antibody; SLY1 antibody; SLY1 homolog antibody; Sly1p antibody; STXBP1L2 antibody; Syntaxin binding protein 1 like 2 antibody; Syntaxin-binding protein 1-like 2 antibody; Vesicle transport related protein antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Synthesized peptide derived from the C-terminal region of Human SCFD1.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:10000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi.
基因功能參考文獻：
1. Mutation in SCFD1 gene is associated with amyotrophic lateral sclerosis. PMID: 27455348
2. Study shows that the SM protein, Sly1, interacts directly with the conserved oligomeric Golgi (COG) tethering complex; Sly1-COG interaction is mediated by the Cog4 subunit, which also interacts with Syntaxin 5 through a different binding site. PMID: 19536132
亞細胞定位：

Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.
蛋白家族：

STXBP/unc-18/SEC1 family
數據庫鏈接：

HGNC: 20726

KEGG: hsa:23256

STRING: 9606.ENSP00000390783

UniGene: Hs.369168

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