RAB4B Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) RAB4B Polyclonal antibody
Uniprot No.：

P61018
基因名：

RAB4B
別名：

1500031G17Rik antibody; FLJ78649 antibody; MGC52123 antibody; OTTMUSP00000026157 antibody; RAB4B antibody; RAB4B; member RAS oncogene family antibody; RAB4B_HUMAN antibody; Ras related GTP binding protein 4b antibody; Ras related protein Rab 4B antibody; Ras-related protein Rab-4B antibody; Small GTP binding protein RAB4B antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Ras-related protein Rab-4B protein (2-213AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Protein transport. Probably involved in vesicular traffic. Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets.
基因功能參考文獻：
1. real-time RT-PCR assays showed that expressions of MIA and MIA-RAB4B located 35 kb upstream of the deletion, were up-regulated in the polyps compared to the matched mucosa of the proband. MIA-RAB4B, the read-through long non-coding RNA (lncRNA), RAB4B, PIM2 and TAOK1 share common binding site of a microRNA, miR-24, in their 3'UTRs PMID: 28306719
2. Interaction between Rab4b and AP1gamma allows the budding of clathrin-coated vesicles for subsequent traffic to recycling endosomes. PMID: 24006255
3. Data conclude that Rab4b is a new important player in the control of GLUT4 trafficking in adipocyte. PMID: 19590752
亞細胞定位：

Cell membrane; Lipid-anchor; Cytoplasmic side.
蛋白家族：

Small GTPase superfamily, Rab family
數據庫鏈接：

HGNC: 9782

OMIM: 612945

KEGG: hsa:53916

STRING: 9606.ENSP00000469872

UniGene: Hs.631539

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