PSMD12 Antibody

說明書

產品詳情

Uniprot No.：

O00232
基因名：

PSMD12
別名：

26S proteasome non-ATPase regulatory subunit 12 antibody; 26S proteasome regulatory subunit p55 antibody; 26S proteasome regulatory subunit RPN5 antibody; MGC75406 antibody; p55 antibody; proteasome (prosome, macropain) 26S subunit, non ATPase12 antibody; Proteasome 26S non ATPase subunit 12 isoform 2 antibody; PSD12_HUMAN antibody; PSMD12 antibody; Rpn5 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human PSMD12
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity Purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
基因功能參考文獻：
1. we identified six de novo genomic deletions and four de novo point mutations in unrelated individuals with intellectual disability, congenital malformations, ophthalmologic anomalies, feeding difficulties, deafness, and subtle dysmorphic facial features PMID: 28132691
相關疾病：

Stankiewicz-Isidor syndrome (STISS)
蛋白家族：

Proteasome subunit p55 family
數據庫鏈接：

HGNC: 9557

OMIM: 604450

KEGG: hsa:5718

STRING: 9606.ENSP00000348442

UniGene: Hs.4295

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