OTOP1 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) OTOP1 Polyclonal antibody
Uniprot No.：

Q7RTM1
基因名：

OTOP1
別名：

OTOP1 antibody; Proton channel OTOP1 antibody; Otopetrin-1 antibody; hOtop1 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Proton channel OTOP1 protein (414-544AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. Regulates purinergic control of intracellular calcium in vestibular supporting cells. May be involved in sour taste perception in sour taste cells by mediating entry of protons within the cytosol. Also involved in energy metabolism, by reducing adipose tissue inflammation and protecting from obesity-induced metabolic dysfunction.
亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Otopetrin family
數據庫鏈接：

HGNC: 19656

OMIM: 607806

KEGG: hsa:133060

STRING: 9606.ENSP00000296358

UniGene: Hs.534544

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