NPM3 Antibody
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中文名稱：NPM3兔多克隆抗體
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貨號：CSB-PA016018GA01HU
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規(guī)格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：NPM3
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別名：NPM 3 antibody; NPM3 antibody; NPM3_HUMAN antibody; Nub1 antibody; nucleophosmin/nucleoplasmin family, member 3 antibody; nucleophosmin/nucleoplasmin, 3 antibody; Nucleoplasmin 3 antibody; Nucleoplasmin-3 antibody; PORMIN antibody; RGD1565542 antibody; TMEM123 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human NPM3
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning. Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM. Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM.
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基因功能參考文獻：
- Studies indicate that histone chalerones nucleoplasmin (NPM2/NPM3) preferentially associated with histones H2A-H2B in the egg and the nuclear autoantigenic sperm protein (NASP) families. PMID: 22968912
- Characterization of the sperm chromatin decondensation and nucleosome assembly activities of homo- and hetero-oligomers of NPM1,NPM2 and NPM3. PMID: 22362753
- NPM3 lacks intrinsic histone chaperone activity, inhibits histone assembly activity of NPM1 in vitro, and dramatically enhances transcription in a cellular system. PMID: 20073534
- Acetylation of transition protein 2 (TP2) by KAT3B (p300) alters its DNA condensation property and interaction with putative histone chaperone NPM3. PMID: 19710011
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亞細胞定位：Nucleus. Nucleus, nucleolus.
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蛋白家族：Nucleoplasmin family
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組織特異性：Ubiquitous.
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數據庫鏈接：
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