NAGK Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) NAGK Polyclonal antibody
Uniprot No.：

Q9UJ70
基因名：

NAGK
別名：

EC 2.7.1.59 antibody; GlcNAc kinase antibody; GNK antibody; HSA242910 antibody; N acetylglucosamine kinase antibody; N-acetyl-D-glucosamine kinase antibody; N-acetylglucosamine kinase antibody; nagK antibody; NAGK_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human N-acetyl-D-glucosamine kinase protein (2-344AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，NAGK Antibody (CSB-PA883457HA01HU)，的標記方式是Non-conjugated。對于NAGK Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA883457HB01HU	NAGK Antibody, HRP conjugated	ELISA
FITC	CSB-PA883457HC01HU	NAGK Antibody, FITC conjugated
Biotin	CSB-PA883457HD01HU	NAGK Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Converts endogenous N-acetylglucosamine (GlcNAc), a major component of complex carbohydrates, from lysosomal degradation or nutritional sources into GlcNAc 6-phosphate. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. Also has ManNAc kinase activity.
基因功能參考文獻：
1. Data shows associations between NAGK, speckle, paraspeckle and general transcription factor suggesting its regulatory roles in gene expression. PMID: 25921606
2. Participants with homozygous mutations in the N-acetylmannosamine kinase (GNK) domain have an earlier disease onset than heterozygous participants with mutations in the uridine diphosphate-N-acetylglucosamine 2-epimerase (GNE) and GNK domains. PMID: 22507750
3. The cell-free system was validated for MNK activity, and it revealed that mutations in one enzymatic domain (in MNK, A631V, M712T) affected not only that domain's enzyme activity, but also the activity of the other domain. PMID: 15987957
4. Phosphorylation of Tyr205 may modulate GlcNAc kinase activity and/or specificity. PMID: 17010375
蛋白家族：

Eukaryotic-type N-acetylglucosamine kinase family
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 17174

OMIM: 606828

KEGG: hsa:55577

STRING: 9606.ENSP00000389087

UniGene: Hs.7036

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