MT1F Antibody, Biotin conjugated

說明書

中文名稱：

MT1F兔多克隆抗體, Biotin偶聯(lián)
貨號：

CSB-PA17409D0Rb
規(guī)格：

￥880
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) MT1F Polyclonal antibody
Uniprot No.：

P04733
基因名：

MT1F
別名：

MT1F antibody; PRO0376 antibody; Metallothionein-1F antibody; MT-1F antibody; Metallothionein-IF antibody; MT-IF antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Metallothionein-1F protein (1-61AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
基因功能參考文獻(xiàn)：
1. we found that metallothionein expression induced by Cd occurred much later, with the expression seen at least 12h or more after the Nrf2-dependent immediate responses were almost completed. PMID: 24440467
2. Metallothionein may have a role in the control of apoptosis in pleomorphic adenoma. PMID: 23332881
3. Aortic protection in diabetes by zinc supplementation is associated with upregulation of both metallothionein and Nrf2 expression. PMID: 23536959
4. findings show 5 MT isoforms were overexpressed in non-small cell lung cancer and overexpression of MT-1F and MT-2A predicted poor outcome; both isoforms may be involved in progression of this cancer type; upregulated MT-1F expression associated with larger primary tumor size and higher grade of malignanacy PMID: 23064051
5. MT1F is a putative tumor suppressor gene in colon carcinogenesis that is downregulated mainly by loss of heterozygosity in colon cancer tissue PMID: 22426038
6. This study identifies for the first time the relevant metallothionein isoforms for colorectal cancer progression. PMID: 21820154
7. Studies provide the mechanistic properties of metal binding for metallothionein metallation. PMID: 21409206
8. MT-1 rs8052394 A allele is associated with oral squamous cell carcinoma. PMID: 21128001
9. In the liver cancer tissue, MT1F shows down-regulated expression that supports the inhibited function of MT1F in cancer growth PMID: 15369632
10. Knockdown of MT1F gene increased particular matter(2.5)-induced H2O2 release in alveolar macrophages. PMID: 19251948
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蛋白家族：

Metallothionein superfamily, Type 1 family
數(shù)據(jù)庫鏈接：

HGNC: 7398

OMIM: 156352

KEGG: hsa:4494

STRING: 9606.ENSP00000334872

UniGene: Hs.513626

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