MND1 Antibody

說明書

產(chǎn)品詳情

產(chǎn)品描述：

The MND1 polyclonal antibody is raised in rabbits and specifically recognizes and binds to the human MND1 protein. The immunogen used to generate this antibody is the recombinant human MND1 protein consisting of 2-205 amino acids. After immunization, the antibody was collected and isolated from the rabbit serum and then purified through protein G chromatography. Its purity reaches 95%⁺.

This MND1 antibody can react with human samples, and it has been extensively tested in various applications such as ELISA, WB, and IHC. Therefore, the MND1 polyclonal antibody can be used to investigate the expression, localization, and activity of MND1 in various experimental contexts.
產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) MND1 Polyclonal antibody
Uniprot No.：

Q9BWT6
基因名：

MND1
別名：

MND1 antibody; GAJ antibody; Meiotic nuclear division protein 1 homolog antibody
宿主：

Rabbit
反應種屬：

Human, Mouse
免疫原：

Recombinant Human Meiotic nuclear division protein 1 homolog protein (2-205AA)
免疫原種屬：

Homo sapiens (Human)
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

Antigen?affinity?purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.02% sodium azide
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產(chǎn)品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:3000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
基因功能參考文獻：
1. Data indicate that the positive expression of studied genes fertilization rate for GAPDHS positive subset was 66%, ACR - 71%, SPATA22 - 68%, MND1 - 70%, pregnancy rates were 8%, 6%, 18% and 36% respectively. PMID: 23675907
2. Data suggest that the human TBPIP/Hop2-Mnd1 complex may ensure proper pairing between homologous chromosomes through its stimulation of strand exchange during meiosis. PMID: 16407260
亞細胞定位：

Nucleus.
蛋白家族：

MND1 family
數(shù)據(jù)庫鏈接：

HGNC: 24839

OMIM: 611422

KEGG: hsa:84057

STRING: 9606.ENSP00000240488

UniGene: Hs.294088

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