MAP1LC3C Antibody, HRP conjugated
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中文名稱：MAP1LC3C兔多克隆抗體, HRP偶聯
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貨號：CSB-PA887153LB01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) MAP1LC3C Polyclonal antibody
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Uniprot No.：
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基因名：MAP1LC3C
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別名：ATG8J antibody; Autophagy-related protein LC3 C antibody; Autophagy-related ubiquitin-like modifier LC3 C antibody; LC3 like protein 2 antibody; MAP1 light chain 3 like protein 2 antibody; MAP1 light chain 3 like protein 3 antibody; MAP1 light chain 3-like protein 3 antibody; MAP1A/MAP1B LC3 C antibody; MAP1A/MAP1B light chain 3 C antibody; MAP1LC3C antibody; Microtubule-associated protein 1 light chain 3 gamma antibody; Microtubule-associated proteins 1A/1B light chain 3C antibody; MLP3C_HUMAN antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Microtubule-associated proteins 1A/1B light chain 3C protein (1-30AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins.
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基因功能參考文獻：
- a basal, housekeeping mitophagy pathway that involves piecemeal degradation of mitochondrial proteins in a LC3C- and p62-dependent manner and contributes to mitochondrial homeostasis maintenance when cells rely on oxidative phosphorylation. PMID: 29149599
- a non-canonical autophagy pathway reminiscent of LC3-associated phagocytosis contributes to Vpu counteraction of BST2 restriction. PMID: 27880899
- The WDR81 interacts with LC3C through canonical LC3-interacting regions in the BEACH domain, promoting LC3C recruitment to ubiquitinated proteins. PMID: 28404643
- Results indicate that TECPR2 Binds LC3and the complex is required for autophagosome formation, possibly through regulation of functional ER exit sites PMID: 26431026
- both autophagy-related 5 and microtubule-associated protein 1 light chain 3B levels are decreased in patients with melanomas as compared with those with benign nevi PMID: 24300435
- ccytoplasm against Salmonella. PMID: 23022382
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亞細胞定位：Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome. Note=LC3-II binds to the autophagic membranes.
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蛋白家族：ATG8 family
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組織特異性：Most abundant in placenta, lung and ovary.
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數據庫鏈接：
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