Lypla1 Antibody, Biotin conjugated

說明書

中文名稱：

Lypla1兔多克隆抗體, Biotin偶聯(lián)
貨號(hào)：

CSB-PA013268LD01MO
規(guī)格：

￥880
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Mus musculus (Mouse) Lypla1 Polyclonal antibody
Uniprot No.：

P97823
基因名：

Lypla1
別名：

Lypla1 antibody; Apt1 antibody; Pla1a antibody; Acyl-protein thioesterase 1 antibody; APT-1 antibody; EC 3.1.2.- antibody; Lysophospholipase 1 antibody; Lysophospholipase I antibody; LPL-I antibody; LysoPLA I antibody
宿主：

Rabbit
反應(yīng)種屬：

Mouse
免疫原：

Recombinant Mouse Acyl-protein thioesterase 1 protein (1-230AA)
免疫原種屬：

Mus musculus (Mouse)
標(biāo)記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Could also depalmitoylate ADRB2. Acts as a lysophospholipase hydrolyzing various lysophospholipids including lysophosphatidylcholine (lyso-PC), lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS)(PubMed:9139730). Has much higher thioesterase activity than lysophospholipase activity. Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA.
基因功能參考文獻(xiàn)：
1. Lyplal1 is dispensable for normal mouse metabolic physiology. PMID: 29084768
2. Data indicate that thioesterases APT1/APT2 depalmitoylate nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) and zDHHC17 is the strongest candidate palmitoyltransferase for NMNAT2. PMID: 25271157
3. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43 PMID: 23396970
亞細(xì)胞定位：

Cytoplasm. Cell membrane. Nucleus membrane. Endoplasmic reticulum.
蛋白家族：

AB hydrolase superfamily, AB hydrolase 2 family
數(shù)據(jù)庫鏈接：

KEGG: mmu:18777

STRING: 10090.ENSMUSP00000027036

UniGene: Mm.299955

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