LMBR1L Antibody
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中文名稱：LMBR1L兔多克隆抗體
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貨號：CSB-PA012996GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：LMBR1L
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別名：LMBR1L antibody; KIAA1174 antibody; LIMR antibody; UNQ458/PRO783Protein LMBR1L antibody; Limb region 1 protein homolog-like antibody; Lipocalin-1-interacting membrane receptor antibody; LIMR antibody
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反應種屬：Human,Mouse,Rat
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免疫原：Human LMBR1L
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plays an essential role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway. In association with UBAC2 and E3 ubiquitin-protein ligase AMFR, promotes the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6. LMBR1L stabilizes the beta-catenin destruction complex that is required for regulating CTNNB1 levels. Acts as a LCN1 receptor and can mediate its endocytosis.
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基因功能參考文獻：
- LIMR was shown to be highly specific for Lcn1, binding the lipocalin with low micromolar to high nanomolar affinity PMID: 23964685
- The receptor to which lipocalin binds is termed tear lipocalin-interacting membrane receptor and it appears to work by endocytosis. PMID: 21791187
- LIMR mediating internalization of lipocalin-1 (Lcn-1) in NT2 cells, leading to its degradation. PMID: 12591932
- Human LIMR, known to act as an endocytic receptor for lipocalin-1, also binds bovine BLG and mediates its cellular uptake. PMID: 17991420
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亞細胞定位：Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
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蛋白家族：LIMR family
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組織特異性：Expressed in testis, pituitary gland, adrenal gland, trachea, placenta, thymus, cerebellum, stomach, mammary gland, spinal cord. A weaker expression is detected in colon, pancreas, and prostate.
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數據庫鏈接：
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