KIF13A Antibody, FITC conjugated
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中文名稱：KIF13A兔多克隆抗體, FITC偶聯
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貨號：CSB-PA880944LC01HU
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規格：￥880
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) KIF13A Polyclonal antibody
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Uniprot No.：
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基因名：KIF13A
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別名：bA500C11.2 antibody; FLJ27232 antibody; Homolog of mouse KIF13A mannose 6 phosphate receptor transporter antibody; KI13A_HUMAN antibody; KIF 13A antibody; Kif13a antibody; Kinesin family member 13A antibody; Kinesin like protein KIF13A antibody; Kinesin like protein RBKIN antibody; Kinesin-like protein KIF13A antibody; Kinesin-like protein RBKIN antibody; RBKIN antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Kinesin-like protein KIF13A protein (1383-1537AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.
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基因功能參考文獻：
- the crystal structure of a catalytically active kinesin-13 monomer (Kif2A) in complex with two bent alphabeta-tubulin heterodimers in a head-to-tail array, providing a view of these interactions, is reported. PMID: 29980677
- that KIF13A plays an important role in the transport of influenza A viral ribonucleoproteins PMID: 29061883
- KIF13A interacts and cooperates with RAB11 to generate endosomal tubules. PMID: 24462287
- kjh kiiou ouiy 8yt 8iy 7i9y PMID: 24859087
- the kinesin-13 MCAK has an unconventional ATPase cycle adapted for microtubule depolymerization PMID: 21873978
- Functionally characterizes the homologous mouse protein. PMID: 11106728
- PtdIns(3)P production is essential for proper cytokinesis. PtdIns(3)P-binding centrosomal protein FYVE-CENT and TTC19 control cytokinesis through their translocation from the centrosome to the midbody mediated by the kinesin protein KIF13A. PMID: 20208530
- show that the clathrin adaptor AP-1 and the kinesin motor KIF13A together create peripheral recycling endosomal subdomains in melanocytes required for cargo delivery to maturing melanosomes. PMID: 19841138
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亞細胞定位：Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Endosome membrane. Golgi apparatus membrane. Note=Recruited to the midbody during cytokinesis.
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蛋白家族：TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
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組織特異性：Widely expressed, with highest levels in heart, brain and skeletal muscle.
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數據庫鏈接：
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