IVNS1ABP Antibody, Biotin conjugated
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中文名稱：IVNS1ABP兔多克隆抗體, Biotin偶聯(lián)
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貨號：CSB-PA896937LD01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) IVNS1ABP Polyclonal antibody
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Uniprot No.：
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基因名：IVNS1ABP
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別名：IVNS1ABP antibody; ARA3 antibody; FLARA3 antibody; KIAA0850 antibody; KLHL39 antibody; NS1 antibody; NS1BP antibody; HSPC068 antibody; Influenza virus NS1A-binding protein antibody; NS1-BP antibody; NS1-binding protein antibody; Aryl hydrocarbon receptor-associated protein 3 antibody; Kelch-like protein 39 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Influenza virus NS1A-binding protein (401-642AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Biotin
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro).; (Microbial infection) Involved in the alternative splicing of influenza A virus M1 mRNA through interaction with HNRNPK, thereby facilitating the generation of viral M2 protein.
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基因功能參考文獻(xiàn)：
- Data show that heterogeneous nuclear ribonucleoprotein K (hnRNP K) and influenza virus NS1A binding protein (NS1-BP) regulate host splicing events and that viral infection causes mis-splicing of some of these transcripts. PMID: 29921878
- Our study identifies KLHL39 as a negative regulator of Cul3-KLHL20 ubiquitin ligase and reveals a role of KLHL39-mediated PML and DAPK stabilization in colon cancer metastasis. PMID: 25619834
- NS1-BP-hnRNPK complex is a key mediator of influenza A virus gene expression. PMID: 23825951
- This study provided evidence that miRNA-548an is involved in the regulation of NS1ABP. PMID: 24210102
- These findings further support the distinct roles of alpha-enolase and its MBP-1 variant in maintaining cell homeostasis. Moreover, these data suggest a novel function for NS1-BP in the control of cell proliferation. PMID: 17996313
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亞細(xì)胞定位：Cytoplasm. Cytoplasm, cytoskeleton. Nucleus, nucleoplasm.
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數(shù)據(jù)庫鏈接：
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