HOXD8 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

P13378
基因名：

HOXD8
別名：

homeo box 4E antibody; homeo box D8 antibody; Homeobox 4E antibody; homeobox D8 antibody; homeobox protein 5.4 antibody; Homeobox protein Hox-4E antibody; Homeobox protein Hox-5.4 antibody; Homeobox protein Hox-D8 antibody; Hox-4.5 antibody; Hox-4.5, mouse, homolog of antibody; Hox-4E antibody; Hox-5.4 antibody; HOX4 antibody; HOX4E antibody; Hoxd8 antibody; HXD8_HUMAN antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Synthesized peptide derived from the C-terminal region of Human HoxD8.
免疫原種屬：

Homo sapiens (Human)
標記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應用范圍：

WB, ELISA

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:40000

Protocols：

Western Blotting (WB) Protocol
ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
基因功能參考文獻：
1. HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer PMID: 28457970
2. microRNA-520a-3p inhibits proliferation and cancer stem cell phenotype by targeting HOXD8 in non small cell lung cancer cells and restoration of microRNA-520a-3p might be a therapeutic strategy to reverse gefitinib resistance. PMID: 27748920
3. Prox1 and HoxD8 play important roles in the maturation and maintenance of lymphatic vessels. PMID: 19825936
亞細胞定位：

Nucleus.
蛋白家族：

Antp homeobox family
數(shù)據(jù)庫鏈接：

HGNC: 5139

OMIM: 142985

KEGG: hsa:3234

STRING: 9606.ENSP00000315949

UniGene: Hs.301963

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