GPX7 Antibody

中文名稱：

GPX7兔多克隆抗體
貨號：

CSB-PA009872LA01HU
規格：

￥440
圖片：
Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA009872LA01HU at dilution of 1:100
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) GPX7 Polyclonal antibody
Uniprot No.：

Q96SL4
基因名：

GPX7
別名：

CL683 antibody; FLJ14777 antibody; Glutathione peroxidase 7 antibody; GPx-7 antibody; GPX6 antibody; GPX7 antibody; GPX7_HUMAN antibody; GSHPx-7 antibody; NPGPx antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Glutathione peroxidase 7 protein (28-187AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，GPX7 Antibody (CSB-PA009872LA01HU)，的標記方式是Non-conjugated。對于GPX7 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA009872LB01HU	GPX7 Antibody, HRP conjugated	ELISA
FITC	CSB-PA009872LC01HU	GPX7 Antibody, FITC conjugated
Biotin	CSB-PA009872LD01HU	GPX7 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IHC

推薦稀釋比：

Application	Recommended Dilution
IHC	1:20-1:200

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

功能：

It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.
基因功能參考文獻：
1. SNPs most associated with Chemotherapy-induced peripheral neuropathy were in ATP-binding cassette sub-family C member 4 (ABCC4) gene. PMID: 25586538
2. Loss of glutathione peroxidase 7 promotes TNF-alpha-induced NF-kappaB activation in Barrett's carcinogenesis. PMID: 24692067
3. GPx7 promotes oxidative protein folding, directly utilizing Ero1alpha-generated hydrogen peroxide in the early secretory compartment. PMID: 23919619
4. tumour suppressor functions in esophageal adenocarcinomas and silenced by location-specific promoter DNA methylation PMID: 23580780
5. NPGPx protects against fat accumulation in mice and human via modulating ROS PMID: 23828861
6. GPx7 is an unusual CysGPx catalyzing the peroxidatic cycle by a one Cys mechanism in which GSH and PDI are alternative substrates. PMID: 23454490
7. NPGPx is essential for releasing excessive ER stress by enhancing GRP78 chaperone activity to maintain physiological homeostasis. PMID: 23123197
8. GPx7 labeled as secreted glutathione peroxidase, is actually endoplasmic reticulum-resident protein disulfide isomerase peroxidase PMID: 21215271
9. NPGPx plays an essential role in breast cancer cells in alleviating oxidative stress generated from polyunsaturated fatty acid metabolism PMID: 15294905
顯示更多

收起更多
相關疾病：

Barrett esophagus (BE)
亞細胞定位：

Secreted.
蛋白家族：

Glutathione peroxidase family
組織特異性：

Expressed in esophageal epithelial cells; expression is up-regulated after exposure to acidic bile acids.
數據庫鏈接：

HGNC: 4559

OMIM: 614266

KEGG: hsa:2882

STRING: 9606.ENSP00000354677

UniGene: Hs.43728

Most popular with customers

Phospho-YAP1 (S127) Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
XRCC5 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC, IF

Species Reactivity: Human
XDH Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WT1 Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human
WFDC2 Recombinant Monoclonal Antibody

Applications: ELISA, WB, FC

Species Reactivity: Human
WDR5 Recombinant Monoclonal Antibody

Applications: ELISA, IHC, FC

Species Reactivity: Human
VIM Recombinant Monoclonal Antibody

Applications: ELISA, IHC, IF

Species Reactivity: Human
VDR Recombinant Monoclonal Antibody

Applications: ELISA, WB, IHC

Species Reactivity: Human