GATAD2B Antibody, HRP conjugated
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中文名稱：GATAD2B兔多克隆抗體, HRP偶聯(lián)
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貨號(hào)：CSB-PA823905LB01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) GATAD2B Polyclonal antibody
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Uniprot No.：
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基因名：GATAD2B
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別名：FLJ37346 antibody; GATA zinc finger domain containing 2B antibody; GATA zinc finger domain containing protein 2B antibody; GATA zinc finger domain-containing protein 2B antibody; GATAD2B antibody; KIAA1150 antibody; MGC138257 antibody; MGC138285 antibody; mKIAA1150 antibody; p66/p68 antibody; P66B_HUMAN antibody; P66beta antibody; RGD1308533 antibody; transcription repressor p66 beta component of the MeCP1 complex antibody; Transcriptional repressor p66 beta antibody; Transcriptional repressor p66-beta antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Transcriptional repressor p66-beta protein (58-146AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：HRP
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2A. Targets MBD3 to discrete loci in the nucleus. May play a role in synapse development.
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基因功能參考文獻(xiàn)：
- GATAD2B interacts with C-MYC to enhance KRAS driven tumor growth. PMID: 30013058
- This data suggests that 1q21.3 microdeletion is a recurrent microdeletion syndrome with distinguishable phenotypes, and loss of function of GATAD2B is the major contributor of the characteristic facies and ID. PMID: 28211977
- findings suggest that GATAD2B serves as an important mediator of progesterone-progesterone receptor suppression of proinflammatory and contractile genes during pregnancy; decreased GATAD2B expression near term may contribute to the decline in progesterone receptor function, leading to labor PMID: 28576827
- This is the first report of GATAD2B in Chinese ID patients. Our findings will broaden the spectrum of GATAD2B mutations and facilitate genetic diagnosis and counseling. PMID: 28077840
- p66beta might be important for the regulation of LOX in the nucleus. PMID: 25118846
- Detailed clinical description showed that all four individuals with a GATAD2B aberration had a distinctive phenotype with childhood hypotonia, severe intellectual disability. PMID: 23644463
- identification as potent transcriptional repressors interacting with MBD2 and MBD3 PMID: 12183469
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相關(guān)疾病：Mental retardation, autosomal dominant 18 (MRD18)
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亞細(xì)胞定位：Nucleus speckle.
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組織特異性：Widely expressed.
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數(shù)據(jù)庫(kù)鏈接：
