ELMOD2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) ELMOD2 Polyclonal antibody
Uniprot No.：

Q8IZ81
基因名：

ELMOD2
別名：

9830169G11Rik antibody; ELMD2_HUMAN antibody; ELMO domain containing 2 antibody; ELMO domain containing protein 2 antibody; ELMO domain-containing protein 2 antibody; ELMO/CED 12 domain containing 2 antibody; ELMOD2 antibody; MGC10084 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human ELMO domain-containing protein 2 protein (82-200AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.
基因功能參考文獻：
1. The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 resulted in loss of GAP activity. PMID: 24616099
2. TLR3 pathway is dependent on ELMOD2 PMID: 19966137
3. results suggest ELMOD2 as a novel candidate gene for susceptibility in familial idiopathic pulmonary fibrosis PMID: 16773575
4. Results describe the purification from bovine testis of an Arl2 GAP and its identity as ELMOD2, a protein with no previously described function. PMID: 17452337
組織特異性：

Alveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed in alveolar macrophag
數據庫鏈接：

HGNC: 28111

OMIM: 610196

KEGG: hsa:255520

STRING: 9606.ENSP00000326342

UniGene: Hs.450105

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