EBF2 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) EBF2 Polyclonal antibody
Uniprot No.：

Q9HAK2
基因名：

EBF2
別名：

EBF2 antibody; COE2Transcription factor COE2 antibody; Early B-cell factor 2 antibody; EBF-2 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Transcription factor COE2 protein (53-254AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'.
基因功能參考文獻：
1. EBF2 gene variants can contribute to KD [ Kawasaki disease]in the Korean population. PMID: 29749135
2. Novel inguinal hernia susceptibility genes are identified as EFEMP1, WT1, EBF2 and ADAMTS6. PMID: 26686553
3. Blnc1 forms a ribonucleoprotein complex with transcription factor EBF2 to stimulate the thermogenic gene program. Further, Blnc1 itself is a target of EBF2, thereby forming a feedforward regulatory loop to drive adipogenesis toward thermogenic phenotype. PMID: 25002143
4. EBF2 as a mediator of osteoprotegerin inhibition to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. PMID: 19671856
亞細胞定位：

Nucleus.
蛋白家族：

COE family
數據庫鏈接：

HGNC: 19090

OMIM: 609934

KEGG: hsa:64641

STRING: 9606.ENSP00000430241

UniGene: Hs.491292

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