DTX4 Antibody

中文名稱：

DTX4兔多克隆抗體
貨號：

CSB-PA764784LA01HU
規格：

￥440
圖片：
Immunofluorescent analysis of HepG2 cells using CSB-PA764784LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
其他：

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) DTX4 Polyclonal antibody
Uniprot No.：

Q9Y2E6
基因名：

DTX4
別名：

Deltex4 antibody; Dtx4 antibody; DTX4_HUMAN antibody; E3 ubiquitin-protein ligase DTX4 antibody; Protein deltex-4 antibody; RING finger protein 155 antibody; RNF155 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human E3 ubiquitin-protein ligase DTX4 protein (167-432AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，DTX4 Antibody (CSB-PA764784LA01HU)，的標記方式是Non-conjugated。對于DTX4 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA764784LB01HU	DTX4 Antibody, HRP conjugated	ELISA
FITC	CSB-PA764784LC01HU	DTX4 Antibody, FITC conjugated
Biotin	CSB-PA764784LD01HU	DTX4 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, IF

推薦稀釋比：

Application	Recommended Dilution
IF	1:50-1:200

Protocols：

ELISA Protocol
Immunofluorescence (IF) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.
基因功能參考文獻：
1. Notch is ligand activated and undergoes DTX4-mediated ubiquitylation and bilateral endocytosis before ADAM10 processing PMID: 28611181
2. Our results provide molecular insight into the mechanisms by which NLRP4-DTX4 targets TBK1 for degradation. PMID: 22388039
亞細胞定位：

Cytoplasm.
蛋白家族：

Deltex family
數據庫鏈接：

HGNC: 29151

OMIM: 616110

KEGG: hsa:23220

STRING: 9606.ENSP00000227451

UniGene: Hs.523696

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本司產品僅用于科研，不用于臨床診斷和治療

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