CCNG1 Antibody
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中文名稱：CCNG1兔多克隆抗體
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貨號(hào)：CSB-PA004820GA01HU
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規(guī)格：￥3,900
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其他：
產(chǎn)品詳情
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Uniprot No.：
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基因名：
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別名：CCNG 1 antibody; CCNG antibody; CCNG1 antibody; CCNG1_HUMAN antibody; CYCG1 antibody; Cyclin G antibody; Cyclin G1 antibody; Cyclin-G antibody; Cyclin-G1 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human,Mouse,Rat
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免疫原：Human CCNG1
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA,WB,IHC
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Protocols：
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儲(chǔ)存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
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基因功能參考文獻(xiàn)：
- miR-516b functions as a tumor suppressor by directly modulating CCNG1 expression in esophageal squamous carcinoma cells. PMID: 30119241
- Low CCNG1 expression is associated with cancer. PMID: 29787434
- Data show that the miR-27b/cyclin G1 protein (CCNG1)/p53 tumor suppressor protein (P53)/miR-508-5p axis plays important roles in gastric cancer (GC)-associated multidrug resistance (MDR). PMID: 26623719
- Results show that miR-23b may inhibit epithelial ovarian tumorigenesis and progression by targeting CCNG1 and modulating the expression of the relevant genes. PMID: 26872615
- OA induced cell cycle arrest in lung cancer cells through miR-122/Cyclin G1/MEF2D pathway. This finding may contribute to the understanding of the molecular mechanism of OA's anti-tumor activity PMID: 25472877
- Progesterone-induced cyclin G1 mediates the inhibitory effect of progesterone on endometrial epithelial cell proliferation. PMID: 25007270
- cyclin G1 exerts negative control on proliferation of endometrial carcinoma cells (ECCs). PMID: 23589924
- cyclin G1 levels were increased in normal tissue compared with hepatocellular carcinoma tissue and vary over the course of the cell cycle, with equal distribution between the nucleus and cytoplasm. PMID: 22835824
- data suggest that the deficiency of progesterone and its receptors is an important cause of the decreased expression of cyclin G1 in endometrial carcinoma, which may account for carcinogenesis and development of endometrial carcinomas PMID: 22649121
- Cyclin G1 overexpression enhanced Akt activation through interaction with p85 (regulatory subunit of phosphoinositide 3-kinase) PMID: 22271581
- Expression of cyclin G1 and G2 is strongly associated with nasopharyngeal carcinoma cell differentiation. PMID: 21688120
- Loss of microRNA 122 expression in patients with hepatitis B enhances hepatitis B virus replication through cyclin G(1) -modulated P53 activity. PMID: 22105316
- Low expression of P27(kip1) and the high expression of cyclin G in patients acute leukemia may have some correlation with genesis and development of the disease. PMID: 19698214
- cyclin G1 has growth inhibitory activity that is mechanistically linked to ARF-p53 and pRb tumor suppressor pathways. PMID: 12556559
- does not increase significantly during colorectal carcinogenesis and during later metastasis to lymph nodes. PMID: 12684677
- cyclin G has a role in ATM-dependent p53 regulation and in cell cycle regulation during DNA damage PMID: 15077171
- cyclin G1 is a target of miR-122a in human hepatocellular carcinoma PMID: 17616664
- the cyclin box has a role in the proteasome-mediated degradation of cyclin G1 PMID: 18632610
- The B'alpha1 subunit of the serine/threonine protein phosphatase 2A, which binds to cyclin G1, can stabilize cyclin G1 under unstressed conditions and upon DNA damage, as well as inhibit the ability of cyclin G1 to be ubiquitinated. PMID: 18981217
- Results show that in patients resected for HCC, lower miR-122 levels were associated with a shorter TTR, whereas higher cyclin G1 expression was related to a lower survival, suggesting that miR-122 might represent an effective molecular target for HCC. PMID: 19584283
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亞細(xì)胞定位：Nucleus. Note=DNA replication foci after DNA damage.
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蛋白家族：Cyclin family, Cyclin G subfamily
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組織特異性：High levels in skeletal muscle, ovary, kidney and colon.
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數(shù)據(jù)庫(kù)鏈接：
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