C6 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) C6 Polyclonal antibody
Uniprot No.：

P13671
基因名：

C6
別名：

AW111623 antibody; C6 antibody; CO6_HUMAN antibody; Complement component 6 antibody; Complement component C6 antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Complement component C6 protein (521-655AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
基因功能參考文獻：
1. Our study provided novel evidence that genetic variations in complement genes C6 and MASP1were associated with preeclampsia risk, and that the risk varied by preeclampsia subtypes PMID: 27405496
2. recipient C6 rs9200 polymorphism is associated with HCC recurrence after OLT, and improves the predictive value of clinical models. PMID: 27173880
3. Structure of complement C6 suggests a mechanism for initiation and unidirectional, sequential assembly of membrane attack complex (MAC). PMID: 22267737
4. finding of very high serious morbidity in patients with complete C6 deficiency due to meningococcal infections PMID: 22288589
5. Genetic polymorphisms in C6 gene do not influence the risk of aspirin hypersensitivity in Korean asthmatic patients. PMID: 21704099
6. produced by trophoblast cells PMID: 19665237
7. The most common defect, which leads to an increased susceptibility to Neisseria meningitidis infections in the Western Cape, is 879delG. PMID: 17257682
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相關疾病：

Complement component 6 deficiency (C6D)
亞細胞定位：

Secreted.
蛋白家族：

Complement C6/C7/C8/C9 family
數據庫鏈接：

HGNC: 1339

OMIM: 217050

KEGG: hsa:729

STRING: 9606.ENSP00000263413

UniGene: Hs.481992

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