AP1S3 Antibody

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) AP1S3 Polyclonal antibody
Uniprot No.：

Q96PC3
基因名：

AP1S3
別名：

Adapter-related protein complex 1 subunit sigma-1C antibody; Adaptor protein complex AP 1 sigma 1C subunit antibody; Adaptor protein complex AP-1 subunit sigma-1C antibody; Adaptor related protein complex 1 sigma 3 subunit antibody; AP-1 complex subunit sigma-3 antibody; Ap1s3 antibody; AP1S3_HUMAN antibody; Clathrin assembly protein complex 1 sigma-1C small chain antibody; Golgi adaptor HA1/AP1 adaptin sigma-1C subunit antibody; Sigma 1C subunit of AP-1 clathrin antibody; Sigma-adaptin 1C antibody; Sigma1C-adaptin antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human AP-1 complex subunit sigma-3 protein (1-104AA)
免疫原種屬：

Homo sapiens (Human)

標記方式：

Non-conjugated

本頁面中的產品，AP1S3 Antibody (CSB-PA001868EA01HU)，的標記方式是Non-conjugated。對于AP1S3 Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA001868EB01HU	AP1S3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA001868EC01HU	AP1S3 Antibody, FITC conjugated
Biotin	CSB-PA001868ED01HU	AP1S3 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking.
基因功能參考文獻：
1. study demonstrated that AP1S3 interacts with hepatitis C virus E2 and protects it from proteasome-dependent degradation PMID: 27079945
2. AP1S3 silencing disrupted the endosomal translocation of the innate pattern-recognition receptor TLR-3 (Toll-like receptor 3) and resulted in a marked inhibition of downstream signaling. PMID: 24791904
相關疾病：

Psoriasis 15, pustular (PSORS15)
亞細胞定位：

Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
蛋白家族：

Adaptor complexes small subunit family
組織特異性：

Widely expressed.
數據庫鏈接：

HGNC: 18971

OMIM: 615781

KEGG: hsa:130340

STRING: 9606.ENSP00000379891

UniGene: Hs.632555

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