ADAMTS10 Antibody
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中文名稱：ADAMTS10兔多克隆抗體
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貨號：CSB-PA798156
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規格：￥1100
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圖片：
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The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA798156(ADAMTS10 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200) -
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA798156(ADAMTS10 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
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其他：
產品詳情
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Uniprot No.：
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基因名：ADAMTS10
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別名：A disintegrin and metalloproteinase with thrombospondin motifs 10 antibody; A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; 10 antibody; A disintegrin-like and metallopeptidase with thrombospondin type 1 motif; 10 antibody; ADAM metallopeptidase with thrombospondin type 1 motif 10 antibody; ADAM TS10 antibody; ADAM-TS 10 antibody; ADAM-TS10 antibody; ADAMTS-10 antibody; Adamts10 antibody; ATS10_HUMAN antibody; EC 3.4.24 antibody; WMS antibody; WMS1 antibody; zinc metalloendopeptidase antibody
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宿主：Rabbit
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反應種屬：Human,Mouse
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免疫原：Synthetic peptide of Human ADAMTS10
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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抗體亞型：IgG
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純化方式：Antigen affinity purification
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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產品提供形式：Liquid
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應用范圍：ELISA,IHC
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推薦稀釋比：
Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
相關產品
靶點詳情
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功能：Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues.
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基因功能參考文獻：
- Using siRNA, over-expression and mutagenesis, it was found ADAMTS6 inhibits and ADAMTS10 is required for focal adhesions, epithelial cell-cell junction formation, and microfibril deposition. PMID: 27779234
- These findings support the Gly661Arg mutation of ADAMTS10 as the likely cause of POAG in beagles. PMID: 23422823
- ADAMTS10 participates in microfibril biogenesis rather than in fibrillin-1 turnover PMID: 21402694
- ADAMTS10 is a functional metalloprotease as demonstrated by cleavage of alpha2-macroglobulin PMID: 15355968
- Expression in human colonic cell lines. PMID: 15358598
- ADAMTS10 plays a major role in growth and in skin, lens, and heart development in humans. PMID: 15368195
- infer that folding of the complex C-terminal ancillary domain is the rate-limiting step in biosynthesis of ADAMTS10, and that it (but not catalytic domain) is sensitive to subtle changes in efficiency of signal peptide cleavage. PMID: 18567016
- Mutations in ADAMTS10 gene is not responsible for microspherophakia. PMID: 19696795
- Homozygous mutation in ADAMTS10 causes lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. PMID: 19836009
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相關疾病：Weill-Marchesani syndrome 1 (WMS1)
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亞細胞定位：Secreted, extracellular space, extracellular matrix.
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組織特異性：Widely expressed in adult tissues.
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數據庫鏈接：
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