Rat hepatic lipase,HL ELISA Kit
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中文名稱：大鼠肝脂酶(HL)酶聯(lián)免疫試劑盒
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貨號：CSB-E10032r
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規(guī)格：96T/48T
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價格：￥3900/￥2500
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：大鼠肝脂酶(HL)酶聯(lián)免疫試劑盒（CSB-E10032r）為競爭法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的LIPC含量。LIPC即肝脂酶，是血漿脂蛋白代謝關(guān)鍵酶。其背景上參與調(diào)節(jié)高密度脂蛋白膽固醇代謝等。研究機(jī)制方面，主要通過水解甘油三酯和磷脂來調(diào)節(jié)脂蛋白顆粒大小和組成，影響膽固醇逆向轉(zhuǎn)運(yùn)，與心血管疾病等的發(fā)生發(fā)展密切相關(guān)。試劑盒檢測范圍為15.6 pg/mL-1000 pg/mL，可應(yīng)用于肝臟代謝功能研究、脂質(zhì)代謝調(diào)控機(jī)制探索、藥物或營養(yǎng)干預(yù)對HL表達(dá)影響的評估等科研場景，尤其適用于心血管疾病、肥胖癥等代謝相關(guān)疾病的動物模型研究，為體外實(shí)驗(yàn)提供高靈敏度的檢測方案。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名：LipcHepatic triacylglycerol lipase ELISA Kit; HL ELISA Kit; Hepatic lipase ELISA Kit; EC 3.1.1.3 ELISA Kit; Lipase member C ELISA Kit
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縮寫：
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Uniprot No.：
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種屬：Rattus norvegicus (Rat)
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樣本類型：serum, plasma, tissue homogenates
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檢測范圍：15.6 pg/mL-1000 pg/mL
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靈敏度：3.9 pg/mL
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反應(yīng)時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領(lǐng)域：Metabolism
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測定原理：quantitative
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測定方法：Competitive
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數(shù)據(jù)處理：
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貨期：3-5 working days
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles. Also exhibits lysophospholipase activity. Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrates. In native LDL, preferentially hydrolyzes the phosphatidylcholine species containing polyunsaturated fatty acids at sn-2 position.
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亞細(xì)胞定位：Secreted.
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蛋白家族：AB hydrolase superfamily, Lipase family
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數(shù)據(jù)庫鏈接：
STRING: 10116.ENSRNOP00000047403
UniGene: Rn.1195
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