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中文名稱：大鼠繆勒管抑制物質(zhì)/抗繆勒管激素(AMH)酶聯(lián)免疫試劑盒
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貨號：CSB-E11162r
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規(guī)格：96T/48T
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價格：￥3600/￥2500
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促銷：
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：大鼠繆勒管抑制物質(zhì)/抗繆勒管激素(AMH)酶聯(lián)免疫試劑盒（CSB-E11162r）為競爭法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的AMH含量。AMH（抗繆勒管激素）是一種由卵巢和睪丸分泌的激素，對性別分化和生殖系統(tǒng)發(fā)育至關(guān)重要。其研究機制涉及調(diào)節(jié)生殖管道發(fā)育、抑制原始卵泡募集、影響卵巢儲備和生育能力。AMH水平與年齡、卵巢功能和生育狀況密切相關(guān)。試劑盒檢測范圍為0.2 ng/mL-15 ng/mL，適用于生殖生物學、內(nèi)分泌學等領(lǐng)域的科學研究，可用于探索性腺發(fā)育機制、評估生殖相關(guān)疾病模型中的激素水平動態(tài)變化，或用于藥物干預實驗中對AMH表達調(diào)控的效應分析，為深入解析大鼠生殖系統(tǒng)功能提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名：Amh ELISA Kit; Muellerian-inhibiting factor ELISA Kit; Anti-Muellerian hormone ELISA Kit; AMH ELISA Kit; Muellerian-inhibiting substance ELISA Kit; MIS ELISA Kit
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縮寫：
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Uniprot No.：
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種屬：Rattus norvegicus (Rat)
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樣本類型：serum, plasma, tissue homogenates
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檢測范圍：0.2 ng/mL-15 ng/mL
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靈敏度：0.1 ng/mL
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領(lǐng)域：Signal Transduction
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測定原理：quantitative
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測定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.
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標準曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
ng/ml
OD1
OD2
Average
0
2.179
2.234
2.207
0.2
1.752
1.667
1.710
0.6
1.411
1.428
1.420
1.75
0.823
0.829
0.826
5
0.482
0.501
0.491
15
0.264
0.253
0.259
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數(shù)據(jù)處理：
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貨期：3-5 working days
引用文獻
- Kuntai Capsules Improve Premature Ovarian Failure by Regulating AMPK-Mediated Autophagy X Ye, M Chen, J Zhong, H Chen, X Lin,Reproductive Sciences,2025
- Huyang Yangkun formula regulates the mitochondria pathway of ovarian granulosa cell apoptosis through FTO/ m6A-P53 pathway Y Li, L Wang, J Liu, G Nie, H Yang,Frontiers in Pharmacology,2024
- MSCs–derived EVs protect against chemotherapy-induced ovarian toxicity: role of PI3K/AKT/mTOR axis NM Elsherbiny, MS Abdel-Maksoud, K Prabahar,Journal of Ovarian Research,2024
- Negative effects of ethanol on ovarian reserve and endometrium thickness: An animal study E Karaman, ME Aya?,Turk J Obstet Gynecol,2024
- Novel Molecular Mechanisms Underlying the Ameliorative Effect of Platelet-Rich Plasma against Electron Radiation-Induced Premature Ovarian Failure G Demyashkin, M Vadyukhin, Z Murtazalieva,International Journal of Molecular Sciences,2024
- Sildenafil as a Salvage Treatment for Ovarian Torsion: A Rat Model DA Yaginc,/,2023
- Energy Drinks May Affect the Ovarium MM Ismatova,/,2023
- Chronic Fluoride Exposure Induces Ovarian Dysfunction and Potential Association with Premature Ovarian Failure in Female Rats X Tang,Biological trace element research,2023
- Participación del factor inhibitorio de leucemia en los niveles de acetilcolina y en la foliculogénesis ovárica en rata SI Pe?a Díaz,/,2023
- Zuogui pills maintain the stemness of oogonial stem cells and alleviate cyclophosphamide-induced ovarian aging through Notch signaling pathway L Zeng,Phytomedicine,2023
- Altered m6A modification is involved YAP-mediated apoptosis response in 4-vinylcyclohexene diepoxide induced ovotoxicity Y Li,Ecotoxicology and environmental safety,2023
- Melatonin Mitigates Cisplatin-Induced Ovarian Dysfunction via Altering Steroidogenesis, Inflammation, Apoptosis, Oxidative Stress, and PTEN/PI3K/Akt/mTOR/AMPK Signaling Pathway in Female Rats A Al-Shahat,Pharmaceutics,2022
- Mechanistic insights into the protective role of eugenol against stress-induced reproductive dysfunction in female rat model H Helmy,Chemico-biological interactions,2022
- miR-20a Overexpression in Adipose-Derived Mesenchymal Stem Cells Promotes Therapeutic Efficacy in Murine Lupus Nephritis by Regulating Autophagy S Wei,EBioMedicine,2021
- Promising anti- cervical carcinoma and inflammatory agent, Resveratrol targets poly (ADP-ribose) polymerase 1 (PARP-1) induced premature ovarian failure with a potent enzymatic modulatory activity H Alharbi,Journal of Reproductive Immunology,2021
- Impact of Curcumin on Ovarian Reserve After Tubal Ligation: an Experimental Study GD Isgoren,Reproductive Sciences,2021
- Effects of Coenzyme Q10 on Ovarian Surface Epithelium-derived Ovarian Stem Cells and Ovarian Function in 4-vinylcyclohexene Diepoxide-induced Ovarian Failure Mice Hyun Joo Lee,Research Square,2021
- Phytoestrogen genistein hinders ovarian oxidative damage and apoptotic cell death-induced by ionizing radiation: co-operative role of ER-β, TGF-β, and FOXL-2 YH Haddad,Scientific Reports,2020
- CUMS Promotes the Development of Premature Ovarian Insufficiency Mediated by Nerve Growth Factor and Its Receptor in Rats X Fu,BioMed Research International,2020
- Continuous Light-Induced PCOS-Like Changes in Reproduction, Metabolism, and Gut Microbiota in Sprague-Dawley Rats W Chu,Front. Microbiol,2020
- FSH/AMH Ratio and Adipocyte Size are Linked to Ovarian Dysfunction Roberts JA,Endocr. Res,2020
- The regulation of the follicular synchronization and sensitivity of rats with PCOS by AMH during prolonged pituitary downregulation Huang J, et al,Gene,2019
- Prenatal ethanol exposure induces susceptibility to premature ovarian insufficiency Ni Y, et al,Journal of Endocrinology,2019
- Mechanistic perspective of protective effects of resveratrol against cisplatin-induced ovarian injury in rats: emphasis on anti-inflammatory and anti-apoptotic effects Said RS,Naunyn-Schmiedeberg\'s Archives of Pharmacology,2019
- Mechanistic perspective of protective effects of resveratrol against cisplatin-induced ovarian injury in rats: emphasis on anti-inflammatory and anti-apoptotic effects Said RS,Naunyn-Schmiedeberg\'s Archives of Pharmacology,2019
- Umbilical Cord Mesenchymal Stem Cell Transplantation Prevents Chemotherapy-Induced Ovarian Failure via the NGF/TrkA Pathway in Rats Qun Zheng,BioMed Research International,2019
- Effects of VEGF + Mesenchymal Stem Cells and Platelet-Rich Plasma on Inbred Rat Ovarian Functions in Cyclophosphamide-Induced Premature Ovarian Insufficiency Model Vural B,Stem Cell Reviews and Reports,2019
- Effects of VEGF + Mesenchymal Stem Cells and Platelet-Rich Plasma on Inbred Rat Ovarian Functions in Cyclophosphamide-Induced Premature Ovarian Insufficiency Model Vural B,Stem Cell Reviews and Reports,2019
- Assaying Reproductive Capacity in Female Rodents Aiken CE, et al,Methods in Molecular Biology,2018
- Effects of chronic unpredictable mild stress on ovarian reserve in female rats: Feasibility analysis of a rat model of premature ovarian failure Xiao??an Fu.et al,Molecular Medicine Reports,2018
- High-Fat, High-Sugar Diet Disrupts the Pre-ovulatory Hormone Surge and Induces Cystic Ovaries in Cycling Female Rats Katrina M Volk.et al,Journal of the Endocrine Society,2017
- Antimullerian hormone and its receptor gene expression in prenatally androgenized female rats. Daneshian Z.et al,Int J Endocrinol Metab.,2015
- Identification of PCSK9 as a novel serum biomarker for the prenatal diagnosis of neural tube defects using iTRAQ quantitative proteomics. An D.et al,Sci Rep.,2015
- The Effects of Diabetes Mellitus on Ovarian Injury and Reserve: An Experimental Study Nayki U. et al,Gynecol Obstet Invest,2015
- Resveratrol inhibits inflammatory signaling implicated in ionizing radiation-induced premature ovarian failure through antagonistic crosstalk between silencing information regulator 1 (SIRT1) and poly(ADP-ribose) polymerase 1 (PARP-1) Riham Soliman Said.et al,Biochemical Pharmacology,2016
- Kisspeptin is involved in ovarian follicular development during aging in rats Fernandois DD. et al,J Endocrinol,2015
- Exposure of Female Rats to an Environmentally-Relevant Mixture of Brominated Flame Retardants Targets the Ovary, Affecting Folliculogenesis and Steroidogenesis Lef貓vre PL. et al,Biol Reprod,2015
- Evaluation of the effects of fulvestrant and micronized progesterone on the post-operative adhesion formation and ovarian reserve in rat model with ? Oner G. et al,Gynecol Endocrinol,2015
- Suboptimal nutrition in utero causes DNA damage and accelerated aging of the female reproductive tract Aiken CE et al,FASEB J,2013
- The Biochemical and Histologic Effects of Adnexal Torsion and Early Surgical Intervention to Unwind Detorsion on Ovarian Reserve An Experimental Study Ozler A et al,Reprod Sci.,2013
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靶點詳情
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最新研究進展：AMH是一種由生殖細胞產(chǎn)生的生長因子，主要參與了性腺的發(fā)育和生殖調(diào)節(jié)。最新研究表明，AMH在女性中發(fā)揮著重要的作用，如參與卵巢生長和發(fā)育、卵泡發(fā)育和成熟、排卵和孕產(chǎn)等過程。此外，AMH在生殖醫(yī)學中也被廣泛應用于卵巢儲備功能評估和IVF治療等方面。近年來，一些新型AMH檢測技術(shù)的研究也為AMH在臨床上的應用提供了更加準確和可靠的方法。
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功能：This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
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基因功能參考文獻：
- The study uncovers a new role for AMH in regulating gonadotrope function and suggests that AMH participates in the postnatal elevation of FSH secretion in females. PMID: 27030385
- AMH increases GnRH-dependent LH pulsatility and secretion, supporting a central action of AMH on GnRH neurons. PMID: 26753790
- Resveratrol reduced antimullerian hormone levels in rat model of polycystic ovary syndrome. PMID: 25667201
- AMH is the first hormone/protein shown to have an inhibitory action on primordial follicle assembly. PMID: 21637711
- In ovaries from adult cycling rats AMH protein is localized in large primary and secondary follicles and not in primordial or small primary follicles, with its highest expression in the largest preantral follicles. PMID: 20816688
- Mullerian inhibiting substance regulates gonadotropin gene expression PMID: 12878721
- MIS inhibits regeneration of Leydig cells in ethylene dimethanesulfonate-treated rats by enhancing apoptotic cell death as well as by decreasing proliferative capacity. PMID: 14585814
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亞細胞定位：Secreted.
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蛋白家族：TGF-beta family
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數(shù)據(jù)庫鏈接：
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