1. These data suggest that ghrelin inhibits myocardial fibrosis, attenuates left ventricular remodeling, and eventually improves cardiac function by adjusting Act A/FS imbalance. PMID: 29113826
2. manifestation of polycystic ovarian syndrome-like phenotype following prenatal exposure to excess androgen is associated with irregularity in expression of the FST gene during the estrus cycle PMID: 28277126
3. Results show that Myostatin and follistatin protein expression is reduced in the long-term hypertrophied myocardium from spontaneously hypertensive rats with heart failure. PMID: 27128567
4. Myogenin, myostatin, and follistatin expression is lower and myogenic regulatory factor (MRF)4 levels higher in spontaneously hypertensive rats (SHR) with heart failure compared to the Wistar-Kyoto strain. PMID: 22464481
5. Expression of follistatin and myostatin mRNA is increased in muscle and subcutaneous fat of sedentary diabetic rats compared with sedentary control rats. PMID: 22332899
6. The ratio of follistatin/myostatin could be used to monitor the progress of target muscle atrophy and recovery. PMID: 22033906
7. Fst expression is necessary for the proliferation of small hepatocytes. PMID: 21826650
8. Effects of training and androgens on MYOPRO and FOLLI concentrations in blood and skeletal muscle, were investigated. PMID: 20801187
9. During chronic heart failure, decreased skeletal muscle trophism is combined with unchanged myostatin and reduced follistatin expression. PMID: 20002838
10. demonstrate that levels of follistatin mRNA show two surges during the estrous cycle; a relationship between ovarian follistatin expression and progesterone secretion is also suggested PMID: 11906933
11. PACAP and GnRH down-regulate follicle-stimulating hormone-beta mRNA levels by stimulating follistatin gene expression. PACAP influences FSH production selectively by a paracrine mechanism through folliculostellate cells that involves follistatin. PMID: 12088867
12. frequency regulation of FSHbeta transcription involves both direct actions of GnRH and indirect effects, via changes in pituitary FS expression PMID: 12193535
13. we studied the expression of follistatin in rat and mouse liver tumors as a possible mechanism to overcome activin growth control, 40% of the tumors displayed increased levels of follistatin mRNA when compared to tumor-surrounding liver tissue. PMID: 12203361
14. follistatin originating from anterior pituitary folliculostellate cells participates in mediating the effects of IL-1beta, glucocorticoids, and other agents on the response of pituitary cells to activins. PMID: 12538636
15. crystal structure of the presumed heparan sulfate-binding domain of follistatin, both alone and in complex with the small heparin analogs sucrose octasulfate and D-myo-inositol hexasulfate PMID: 12867435
16. inhibin is a major regulator of FS, both by transcriptional and nontranscriptional mechanisms. PMID: 14561646
17. Data suggest that betaA- and betaC-activin subunit proteins and follistatin are autocrine growth regulators in regenerating liver and when expressed independently lead to hepatocyte apoptosis or mitosis in a subset of hepatocytes. PMID: 15821113
18. The roles of activin A and follistatin in hepatic fribrogenesis are reported. PMID: 16123203
19. Follistatin was overexpressed while both activin subunits were downregulated in the majority of rat and human liver tumours PMID: 16935389
20. Follistatin mRNA levels increased significantly with GnRH treatment in young animals but were not significantly changed in the middle aged females. PMID: 17344471
21. intron 1 of the follistatin gene has a critical role in mediating Smad-dependent effects of activin and regulating the expression level of this gene PMID: 18184649
22. Activin betaA subunit, follistatin and follistatin-like 3 are expressed in the endometrium of ovariectomized rats and regulated by estrogen replacement PMID: 18781389
23. Fst expression in the pineal gland exhibits a ~20-fold increase at night, reaching levels that are > 16 fold higher than in other tissues. Expression is controlled by an adrenergic-cyclic AMP mechanism. PMID: 19103603

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KEGG: rno:24373

STRING: 10116.ENSRNOP00000015680

UniGene: Rn.162557