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中文名稱：豬白蛋白酶聯免疫試劑盒
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貨號：CSB-E16207p
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規格：96T/48T
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價格：￥3600/￥2500
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其他：
產品詳情
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產品描述：豬白蛋白酶聯免疫試劑盒（CSB-E16207p）為競爭法ELISA試劑盒，定量檢測血清、血漿、尿液樣本中的ALB含量。ALB即白蛋白，是血漿中含量最豐富的蛋白質。它在維持血漿膠體滲透壓、物質運輸等方面有重要作用。在研究機制上，常作為藥物載體，因其能與多種藥物結合，可改變藥物藥代動力學，提高療效，降低毒副作用，在藥物研發等領域受關注。試劑盒檢測范圍為0.03 μg/mL-7000 μg/mL，靈敏度為0.03 μg/mL。該產品廣泛應用于農業科學領域豬只健康狀態監測、生物制藥中豬源成分殘留檢測、食品工業原料溯源分析，以及基礎科研中豬蛋白代謝通路研究、腎臟功能評估等場景。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
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別名：ALBSerum albumin ELISA Kit
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縮寫：
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Uniprot No.：
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種屬：Sus scrofa (Pig)
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樣本類型：serum, plasma, urine
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檢測范圍：0.03 μg/mL-7000 μg/mL
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靈敏度：0.03 μg/mL
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領域：Metabolism
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測定原理：quantitative
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測定方法：Competitive
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of pig albumin in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:100 Average % 90 Range % 87-95 1:200 Average % 93 Range % 90-100 1:400 Average % 90 Range % 85-93 1:800 Average % 89 Range % 82-96 -
回收率：
The recovery of pig albumin spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 96 93-101 EDTA plasma (n=4) 93 89-100 -
標準曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. 
μg/ml OD1 OD2 Average 7000 0.123 0.128 0.126 875 0.327 0.311 0.319 109.4 0.612 0.623 0.618 13.7 0.837 0.845 0.841 1.7 0.950 0.967 0.959 0.2 1.236 1.221 1.229 0.03 1.493 1.518 1.506 0 1.844 1.904 1.874 -
數據處理：
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貨期：3-5 working days
引用文獻
- Immortalization of porcine hepatocytes with a α-1,3-galactosyltransferase knockout background Wang Q, et al,Xenotransplantation,2019
- Cytokine profiles in Tibetan macaques following α-1,3-galactosyltransferase-knockout pig liver xenotransplantation. Xenotransplantation.et al,Xenotransplantation,2017
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靶點詳情
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最新研究進展：白蛋白（ALB）是一種血漿蛋白，具有多種生理功能，如維持血容量、調節血液滲透壓、輸送物質等。近期的研究發現，ALB在多種疾病中起到關鍵作用。在COVID-19疫情中，患者的ALB水平通常下降，并與嚴重程度呈正相關，因此ALB可能作為預后生物標志物有潛在價值。在腎病中，ALB是最常見的蛋白質丟失之一，其下降可能導致腎臟損傷和慢性腎臟病的進展。因此，ALB已成為評估腎臟健康的重要指標。在癌癥中，ALB水平下降與腫瘤發生和惡化有關，因此ALB可能是腫瘤預后評估的潛在生物標志物之一。在營養方面，ALB水平可以用作評估營養狀況的指標，其下降通常與營養不良相關。綜上所述，ALB在不同疾病中發揮著重要作用，并有望成為評估患者預后和健康狀況的重要指標。
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功能：Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma. Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner. The shared binding site between zinc and calcium at residue Asp-272 suggests a crosstalk between zinc and calcium transport in the blood. The rank order of affinity is zinc > calcium > magnesium. Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli. Does not prevent iron uptake by the bacterial siderophore aerobactin.
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亞細胞定位：Secreted.
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蛋白家族：ALB/AFP/VDB family
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組織特異性：Plasma.
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數據庫鏈接：
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