Mouse Tryptase beta-2(TPSB2) ELISA kit

文獻(xiàn)引用 (3) 說明書下載

中文名稱：

小鼠胰蛋白酶β-2(TPSB2)酶聯(lián)免疫試劑盒
貨號：

CSB-EL024128MO
規(guī)格：

96T/48T
價格：

￥3600/￥2500
促銷：
其他：

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產(chǎn)品描述：

小鼠胰蛋白酶β-2(TPSB2)酶聯(lián)免疫試劑盒（CSB-EL024128MO）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的TPSB2含量。TPSB2是重要靶點。它與過敏等免疫反應(yīng)密切相關(guān)，其編碼的類胰蛋白酶在炎癥介質(zhì)釋放等過程發(fā)揮作用。科研聚焦其在疾病發(fā)生發(fā)展機(jī)制及信號通路中的角色，探索以它為標(biāo)靶的藥物研發(fā)，有望為相關(guān)疾病治療帶來新策略。試劑盒檢測范圍為78 pg/mL-5000 pg/mL，本試劑盒通過高特異性抗體對實現(xiàn)精準(zhǔn)捕獲與檢測，適用于肥大細(xì)胞功能研究、炎癥機(jī)制探索、藥物靶點驗證等科研領(lǐng)域。可為體外實驗或動物模型中的TPSB2動態(tài)變化提供可靠數(shù)據(jù)，助力免疫調(diào)控網(wǎng)絡(luò)解析及疾病相關(guān)分子機(jī)制研究。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
別名：

Tpsb2 ELISA Kit; Mcpt6 ELISA Kit; Tryptase beta-2 ELISA Kit; Tryptase-2 ELISA Kit; EC 3.4.21.59 ELISA Kit; Mast cell protease 6 ELISA Kit; mMCP-6 ELISA Kit
縮寫：

TPSB2
Uniprot No.：

P21845
種屬：

Mus musculus (Mouse)
樣本類型：

serum, plasma, tissue homogenates
檢測范圍：

78 pg/mL-5000 pg/mL
靈敏度：

19.5 pg/mL
反應(yīng)時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領(lǐng)域：

Cell Biology
測定原理：

quantitative
測定方法：

Sandwich
精密度：

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.
線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of mouse TPSB2 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
回收率：

The recovery of mouse TPSB2 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
標(biāo)準(zhǔn)曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
數(shù)據(jù)處理：

ELISA操作視頻及標(biāo)曲繪制軟件下載
貨期：

3-5 working days

引用文獻(xiàn)

Neuronal substance P-driven MRGPRX2-dependent mast cell degranulation products differentially promote vascular permeability 長嶺誠和，ナガミネマサカズ,Thesis & Dissertation,2024
Neuronal substance P-driven MRGPRX2-dependent mast cell degranulation products differentially promote vascular permeability M Nagamine, A Kaitani, K Izawa, T Ando,Frontiers in Immunology,2024
Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch Meixiong J,Immunity,2019

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功能：

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. Plays a role in innate immunity.
亞細(xì)胞定位：

Secreted.
蛋白家族：

Peptidase S1 family, Tryptase subfamily
組織特異性：

During embryogenesis, detected primarily in skin.
數(shù)據(jù)庫鏈接：

STRING: 10090.ENSMUSP00000063499

UniGene: Mm.7409

Mouse Tryptase beta-2(TPSB2) ELISA kit

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