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中文名稱：人血血小板衍生生長因子AB(PDGF-AB)酶聯免疫試劑盒
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貨號：CSB-E04701h
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規格：96T/48T
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價格：￥3200/￥2500
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其他：
產品詳情
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產品描述：人血血小板衍生生長因子AB(PDGF-AB)酶聯免疫試劑盒（CSB-E04701h）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的PDGF-AB含量。PDGF-AB是一種由血小板分泌的生長因子，由A和B鏈組成，參與調控纖維母細胞和平滑肌細胞等中胚層來源細胞的增殖和遷移。其研究機制涉及PDGF與PDGFRα和PDGFRβ受體的結合，激活下游信號通路，促進細胞增殖和血管生成。試劑盒檢測范圍為31.25 pg/mL-2000 pg/mL，靈敏度為7.8 pg/mL。適用于體外實驗中對PDGF-AB的定量分析，例如探究心血管疾病模型中的信號通路機制、評估藥物干預對細胞因子表達的影響，或通過組織樣本分析疾病相關分子標志物變化，為細胞生物學、病理學及藥理學研究提供可靠數據支持。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
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縮寫：PDGF-AB
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種屬：Homo sapiens (Human)
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樣本類型：serum, plasma, tissue homogenates
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檢測范圍：31.25 pg/mL-2000 pg/mL
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靈敏度：7.8 pg/mL
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領域：Cancer
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測定原理：quantitative
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測定方法：Sandwich
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.Inter-assay Precision (Precision between assays): CV%<10%Three samples of known concentration were tested in twenty assays to assess. -
線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of human PDGF-AB in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
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回收率：
The recovery of human PDGF-AB spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
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標準曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
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數據處理：
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貨期：3-5 working days
引用文獻
- Differences in injectable platelet-rich fibrin fraction of peripheral blood on the release of TGF-β1 and PDGF-AB S Suryono,Majalah Kedokteran Gigi Indonesia,2023
- A comparative study of the effects of concentrated growth factors in two different forms on osteogenesis in vitro Wang L,Molecular Medicine Reports,2019
- Chitosan scaffold enhances growth factor release in wound healing in von Willebrand disease Periayah MH. et al,Int J Clin Exp Med,2015
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靶點詳情
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最新研究進展：PDGF-AB是血小板源性生長因子（platelet-derived growth factor，PDGF）家族的一個亞型，由PDGF-A和PDGF-B兩個亞基組成。最近的研究表明，PDGF-AB參與了多種生物學過程，如細胞增殖、分化、遷移和細胞外基質合成等。此外，PDGF-AB在多種疾病中也發揮著重要作用，如腫瘤、動脈粥樣硬化和組織損傷等。因此，PDGF-AB成為了治療靶點的研究熱點。一些研究已經探索了PDGF-AB的抑制劑和抗體，以期望發現更有效的治療方案。
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