Human Kynurenine (KYN)ELISA Kit

Human Kynurenine (KYN)ELISA Kit

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中文名稱：

人犬尿氨酸（KYN)酶聯(lián)免疫試劑盒
貨號：

CSB-E13659h
規(guī)格：

96T/48T
價格：

￥3600/￥2500
促銷：
其他：

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產(chǎn)品描述：

人犬尿氨酸（KYN)酶聯(lián)免疫試劑盒（CSB-E13659h）為競爭法ELISA試劑盒，定量檢測血清、尿液、組織勻漿樣本中的KYN含量。試劑盒檢測范圍為7.8 pmol/ml-500 pmol/ml，產(chǎn)品適用于科研場景中KYN代謝機制研究、疾病模型評估及藥物開發(fā)過程中的生物標(biāo)志物檢測，例如探索神經(jīng)系統(tǒng)疾病動物模型的代謝變化或免疫調(diào)節(jié)藥物對色氨酸代謝通路的影響。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
縮寫：

KYN
種屬：

Homo sapiens (Human)
樣本類型：

serum, urine, tissue homogenates
檢測范圍：

7.8 pmol/ml-500 pmol/ml.
靈敏度：

3.9 pmol/ml.
反應(yīng)時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領(lǐng)域：

Metabolism
測定原理：

quantitative
測定方法：

Competitive

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of human KYN in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

	Sample	Serum(n=4)
1:1	Average %	95
	Range %	90-99
1:2	Average %	87
	Range %	84-90
1:4	Average %	92
	Range %	88-96
1:8	Average %	97
	Range %	95-99

回收率：

標(biāo)準(zhǔn)曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

pmol/ml

OD1

OD2

Average

500

0.200

0.202

0.201

250

0.318

0.338

0.328

125

0.498

0.470

0.484

62.5

0.685

0.664

0.675

31.2

1.036

1.016

1.026

15.6

1.468

1.404

1.436

7.8

1.533

1.657

1.595

1.710

1.723

1.717

數(shù)據(jù)處理：

ELISA操作視頻及標(biāo)曲繪制軟件下載
貨期：

3-5 working days

IDO1 inhibition enhances CLDN18.2-CAR-T cell therapy in gastrointestinal cancers by overcoming kynurenine-mediated metabolic suppression in the tumor microenvironment Z Wu, H Wang, Z Zheng, Y Lin, L Bian, H Geng,Journal of Translational Medicine,2025
TDO2 promotes bladder cancer progression via AhR-mediated SPARC/FILIP1L signaling X Ding,Biochemical pharmacology,2024
Improvement of sleep by resistant dextrin prebiotic in type 2 diabetic women coincides with attenuation of metabolic endotoxemia: Involvement of gut‐brain axis S Saleh‐Ghadimi,Journal of the science of food and agriculture,2023
MUC1 Expression Affects the Immunoflogosis in Renal Cell Carcinoma Microenvironment through Complement System Activation and Immune Infiltrate Modulation G Lucarelli,International journal of molecular sciences,2023
Targeting the STAT5A/IDO1 axis overcomes radioresistance and reverses the immunosuppressive tumor microenvironment in NSCLC Y Yang,International journal of oncology,2022
Tryptophan 2, 3-dioxygenase promotes proliferation, migration and invasion of ovarian cancer cells Yuemei Zhao,Molecular Medicine Reports,2021
Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial Asma Kazemi.et al,clinical nutrition,2018
A randomized controlled trial on the efficacy of resistant dextrin, as functional food, in women with type 2 diabetes: Targeting the hypothalamic?pituitary?adrenal axis and immune system Farhangi MA.et al,Clin Nutr,2017
Lung Cancer Associated Fibroblast-Mediated Cancer Progression and Immune Inhibition Through TDO2/Kynurenine Loop Kuo P L.et al,Am J Respir Crit Care Med,2016
Lung cancer-derived galectin-1 contributes to cancer associated fibroblast-mediated cancer progression and immune suppression through TDO2/kynurenine axis Hsu YL.et al,Oncotarget.,2016
Supplement of 5-hydroxytryptophan before induction suppresses inflammation and collagen-induced arthritis Yang TH. et al,Arthritis Res Ther,2015
The effects of probiotics on mental health and hypothalamic-pituitary-adrenal axis: A randomized, double-blind, placebo-controlled trial in petrochemical workers Mohammadi AA et al,Nutr Neurosci,2015

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Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.