Human Immunoglobulin E,IgE ELISA Kit
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中文名稱：人免疫球蛋白E(IgE)酶聯(lián)免疫試劑盒
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貨號：CSB-E04980h
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規(guī)格：96T/48T
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價格：￥3200/￥2500
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：人免疫球蛋白E(IgE)酶聯(lián)免疫試劑盒（CSB-E04980h）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿樣本中的IgE含量。IgE即免疫球蛋白E，是介導(dǎo)Ⅰ型超敏反應(yīng)的抗體。其在過敏反應(yīng)、寄生蟲感染等疾病機(jī)制中作用關(guān)鍵。研究通過分析IgE與效應(yīng)細(xì)胞表面受體結(jié)合過程等機(jī)制，以開發(fā)出針對IgE的療法，如抗IgE單抗，用于治療相關(guān)病癥。試劑盒檢測范圍為62.5 ng/mL-4000 ng/mL，靈敏度為3.640 ng/mL。該產(chǎn)品適用于科研場景下的體外定量分析，例如探究過敏性疾病發(fā)生機(jī)制、評估免疫調(diào)節(jié)藥物干預(yù)效果，或監(jiān)測實驗?zāi)Ｐ椭蠭gE的動態(tài)變化，為免疫學(xué)、藥理學(xué)等領(lǐng)域的相關(guān)研究提供可靠工具。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
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別名：N/A
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縮寫：IgE
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種屬：Homo sapiens (Human)
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樣本類型：serum, plasma
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檢測范圍：62.5 ng/mL-4000 ng/mL
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靈敏度：3.640 ng/mL
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反應(yīng)時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領(lǐng)域：Immunology
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測定原理：quantitative
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測定方法：Sandwich
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays):CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
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線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of human IgE in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
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標(biāo)準(zhǔn)曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
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數(shù)據(jù)處理：
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貨期：3-5 working days
引用文獻(xiàn)
- Evaluation serum levels of IL-4 in common chronic inflammatory respiratory disease NN Mubark,International Journal of Immunology Research,/
- Blood Test for Allergies Related to Environmental Diseases in Households Vulnerable to Indoor Air Quality in Daejeon Metropolitan City HW Seo, JH Oh, SH Baek, SY Hwang,J Environ Health Sci.,2024
- Expression of circulating angiotensin‐converting enzyme 2 in children with asthma and the effects of inhaled corticosteroids X Ma,Immunity, inflammation and disease,2023
- Evaluation the Effect of Phytosterol Fraction of Chenopodium Murale in Comparison with Tacrolimus on Mice Induced Atopic Dermatitis Z Hassan,Iraqi Journal of Pharmaceutical Sciences,2023
- Gamma Irradiation-Inactivated Respiratory Syncytial Virus Vaccine Provides Protection but Exacerbates Pulmonary Inflammation by Switching from Prefusion to Postfusion F Protein F Chen,Microbiology spectrum,2023
- Adipose-derived stem cells decolonize skin Staphylococcus aureus by enhancing phagocytic activity of peripheral blood mononuclear cells in the atopic rats J Lee,The Korean journal of physiology & pharmacology,2022
- The correlation of serum chemokine CCL11, CCL17, CCL26, and CCL27 and disease severity in patients with urticaria/Analysis of serum chemokine levels in patients with HIV-associated eosinophilic folliculitis. Yokobayashi H. et al,J Eur Acad Dermatol Venereol,2013
- A common variant associated with asthma, interleukin 13 R130Q, promotes the production of IgE Chu Y et al,International Journal of Immunogenetics,2012
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靶點詳情
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最新研究進(jìn)展：IgE是一種免疫球蛋白，也稱為過敏素，通常與過敏反應(yīng)相關(guān)。最近的研究表明，IgE在人體內(nèi)除了參與過敏反應(yīng)外，還可能在腫瘤免疫中扮演重要角色。一項發(fā)表于2021年的研究發(fā)現(xiàn)，IgE能夠識別腫瘤細(xì)胞表面的一種糖蛋白，這種糖蛋白被稱為“Tn抗原”，并且通過結(jié)合這種糖蛋白來識別和殺死腫瘤細(xì)胞。這項研究為IgE在腫瘤免疫療法中的應(yīng)用提供了新的思路。
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