Human Ig kappa chain V-IV region(IGKV4-1) ELISA kit

Human Ig kappa chain V-IV region(IGKV4-1) ELISA kit

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中文名稱：

人Igκ鏈V-IV區(IGKV4-1)酶聯免疫試劑盒
貨號：

CSB-EL011443HU
規格：

96T/48T
價格：

￥3600/￥2500
其他：

CUSABIO Wins 2024 Bioz Rapid Star? Award in the ELISA category

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產品描述：

人Igκ鏈V-IV區(IGKV4-1)酶聯免疫試劑盒（CSB-EL011443HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿、細胞裂解物.樣本中的IGKV4-1含量。IGKV4 - 1 是重要的靶點。它在相關疾病的發生發展中可能發揮關鍵作用。研究機制方面，可能涉及到與免疫反應、細胞信號傳導等過程的關聯，通過對其深入研究，有望揭示疾病的發病機制，為開發針對性的治療方案奠定基礎。試劑盒檢測范圍為0.156 ng/ml-10 ng/ml，適用于科研領域中對B細胞功能、抗體生成機制及相關疾病模型的探索，例如免疫失調研究、抗體工程開發或腫瘤微環境分析等場景。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
別名：

IGKV4-1Immunoglobulin kappa variable 4-1 ELISA Kit; Ig kappa chain V-IV region B17 ELISA Kit; Ig kappa chain V-IV region JI ELISA Kit; Ig kappa chain V-IV region Len ELISA Kit; Ig kappa chain V-IV region STH ELISA Kit
縮寫：

IGKV4-1
Uniprot No.：

P06312
種屬：

Homo sapiens (Human)
樣本類型：

serum, plasma, tissue homogenates, cell lysates.
檢測范圍：

0.156 ng/ml -10 ng/ml
靈敏度：

0.039 ng/ml
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Immunology
測定原理：

quantitative
測定方法：

Sandwich

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of human IGKV4-1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

	Sample	Serum(n=4)
1:1	Average %	88
	Range %	81-95
1:2	Average %	96
	Range %	89-103
1:4	Average %	97
	Range %	92-103
1:8	Average %	93
	Range %	86-100

回收率：

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ng/ml

OD1

OD2

Average

Corrected

2.069

2.034

2.051

1.922

1.347

1.367

1.357

1.228

2.5

0.797

0.828

0.812

0.683

1.25

0.428

0.409

0.419

0.289

0.625

0.294

0.311

0.302

0.173

0.312

0.235

0.243

0.239

0.110

0.156

0.157

0.164

0.160

0.031

0.134

0.125

0.130

數據處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

功能：

V segment of the variable domain of immunoglobulins light chain that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
亞細胞定位：

Secreted. Cell membrane.
數據庫鏈接：

HGNC: 5834

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.