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中文名稱：人Ⅰ型膠原交聯羧基末端肽(CTX-I)酶聯免疫試劑盒
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貨號：CSB-E11224h
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規格：96T/48T
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價格：￥3200/￥2500
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其他：
產品詳情
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產品描述：人Ⅰ型膠原交聯羧基末端肽(CTX-I)酶聯免疫試劑盒（CSB-E11224h）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CTX-I含量。試劑盒檢測范圍為0.625 ng/mL-40 ng/mL，常用于骨質疏松機制研究、骨關節疾病模型評估及抗骨吸收藥物開發等科研領域；適用于體外骨代謝標志物檢測、細胞模型骨吸收活性分析及動物實驗樣本評估等非臨床研究場景，為骨生物學研究提供可靠工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
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別名：Cross-linked Carboxy-terminal telopeptide of type 1 collagen, CTX-1, Cross-linked Carboxy-terminal telopeptide of type I collagen, CTX-I
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縮寫：CTX-I
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種屬：Homo sapiens (Human)
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樣本類型：serum, plasma, tissue homogenates
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檢測范圍：0.625 ng/mL-40 ng/mL
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靈敏度：0.156 ng/mL
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反應時間：1-5h
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樣本體積：50-100ul
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檢測波長：450 nm
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研究領域：Others
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測定原理：quantitative
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測定方法：Sandwich
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精密度：
Intra-assay Precision (Precision within an assay): CV%<8% Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV%<10% Three samples of known concentration were tested in twenty assays to assess. -
線性度：
To assess the linearity of the assay, samples were spiked with high concentrations of human CTX-I in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. Sample Serum(n=4) 1:1 Average % 88 Range % 83-95 1:2 Average % 95 Range % 91-98 1:4 Average % 97 Range % 90-103 1:8 Average % 96 Range % 91-101 -
回收率：
The recovery of human CTX-I spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. Sample Type Average % Recovery Range Serum (n=5) 85 81-92 EDTA plasma (n=4) 96 93-106 -
標準曲線：
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. 
ng/ml OD1 OD2 Average Corrected 40 2.995 2.960 2.978 2.838 20 2.557 2.570 2.564 2.424 10 1.666 1.765 1.716 1.576 5 0.839 0.886 0.863 0.723 2.5 0.491 0.524 0.508 0.368 1.25 0.263 0.251 0.257 0.117 0.625 0.201 0.212 0.207 0.067 0 0.138 0.142 0.140 -
數據處理：
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貨期：3-5 working days
引用文獻
- GPR37 Activation Alleviates Bone Cancer Pain via the Inhibition of Osteoclastogenesis and Neuronal Hyperexcitability K Wang, Y Zhang, R Shu, L Yuan, H Tu,Advanced Science,2025
- C-terminal cross-linking telopeptide levels in COVID-19 patients: A prospective case-control study MA Gul,Advances in clinical and experimental medicine,2024
- ERK-estrogen receptor α signaling plays a role in the process of bone marrow mesenchymal stem cell-derived exosomes protecting against ovariectomy-induced bone loss H Qi,Journal of orthopaedic surgery and research,2023
- Effect of polyhydroxy-terminated PAMAM dendrimer on dentin matrix metalloproteinases within the hybrid layers Y Luo,BMC oral health,2023
- Rosiglitazone Mitigates Dexamethasone-Induced Depression in Mice via Modulating Brain Glucose Metabolism and AMPK/mTOR Signaling Pathway A Alhaddad,Biomedicines,2023
- Changes in bone turnover markers in patients without bone metastases receiving immune checkpoint inhibitors: An exploratory analysis F Pantano,Journal of bone oncology,2022
- Praeruptorin B inhibits osteoclastogenesis by targeting GSTP1 and impacting on the S-glutathionylation of IKKβ K Xu,Biomedicine & pharmacotherapy,2022
- TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling W Yang,Bone Research,2021
- Umbilical cord N-terminal procollagen of type l collagen (P1NP) and beta C-terminal telopeptide (βCTX) levels in term pregnancies with vitamin D deficiency M Eraslan Sahin,Journal Gynecological Endocrinology,2020
- Efficacy and Safety of Kudzu Flower–Mandarin Peel on Hot Flashes and Bone Markers in Women during the Menopausal Transition: A Randomized Controlled Trial JE Kim,Nutrients,2020
- Association between bile acid metabolism and bone mineral density in postmenopausal women Zhao YX,Clinics (Sao Paulo),2020
- The inhibitory effect of carboxyl-terminated polyamidoamine dendrimers on dentine host-derived matrix metalloproteinases in vitro in an etch-and-rinse adhesive system Wu Q, et al,Royal Society Open Science,2019
- The Circadian Gene Clock Regulates Bone Formation Via PDIA3 Yuan G.et al,J Bone Miner Res. ,2016
- Effect of Vitamin D on Peripheral Blood Mononuclear Cells from Patients with Psoriasis Vulgaris and Psoriatic Arthritis Cubillos S.et al,PLoS One.,2016
- RANKL/Osteoprotegerin System and Bone Turnover in Hashimoto Thyroiditis. Konca Degertekin C.et al,Calcif Tissue Int.,2016
- Combination Treatment with Whole Body Vibration and a Kidney-tonifying Herbal Fufang Prevent Osteoporosis in Ovariectomized Rats Wei QS et al,Orthop Surg,2015
- Alteration of Cartilage Degeneration and Inflammation Markers in Temporomandibular Joint Osteoarthritis Occurs Proportionally Vos LM et al,J Oral Maxillofac Surg,2013
產品評價
相關問答
■ 常見問題解答
Q:
Please provide the following information regarding Human Cross-linked Carboxy-terminal telopeptide of type I collagen, CTX-I ELISA Kit CSB-E11224h
a. Is the capture antibody a monoclonal or polyclonal?
b. What is the host of the capture antibody?
c. Is the detection antibody a monoclonal or polyclonal?
d. What is the host of the detection antibody?
e. B208. What’s is that standard? A recombinant protein or something else? If a recombinant protein, what is the host?
f. If recombinant protein, is it full length or partial?
g. What is the species of the standard– human or something else?
A:
Thanks for your inquiry.
CSB-E11224h
Capture antibody is mouse monoclonal antibody and detection antibody is goat polyclonal antibody.
Standard is synthetic peptide.
Pls let me know if you have any further questions. Thank you.
CSB-E11224h
Capture antibody is mouse monoclonal antibody and detection antibody is goat polyclonal antibody.
Standard is synthetic peptide.
Pls let me know if you have any further questions. Thank you.
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