Human Cross-linked Carboxy-terminal telopeptide of type Ⅰ collagen, CTX-I ELISA Kit

Human Cross-linked Carboxy-terminal telopeptide of type Ⅰ collagen, CTX-I ELISA Kit

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中文名稱：

人Ⅰ型膠原交聯羧基末端肽(CTX-I)酶聯免疫試劑盒
貨號：

CSB-E11224h
規格：

96T/48T
價格：

￥3200/￥2500
其他：

CUSABIO Wins 2024 Bioz Rapid Star? Award in the ELISA category

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引用文獻
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產品描述：

人Ⅰ型膠原交聯羧基末端肽(CTX-I)酶聯免疫試劑盒（CSB-E11224h）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CTX-I含量。試劑盒檢測范圍為0.625 ng/mL-40 ng/mL，常用于骨質疏松機制研究、骨關節疾病模型評估及抗骨吸收藥物開發等科研領域；適用于體外骨代謝標志物檢測、細胞模型骨吸收活性分析及動物實驗樣本評估等非臨床研究場景，為骨生物學研究提供可靠工具。本品僅用于科研，不用于臨床診斷，產品具體參數及操作步驟詳見產品說明書。
別名：

Cross-linked Carboxy-terminal telopeptide of type 1 collagen, CTX-1, Cross-linked Carboxy-terminal telopeptide of type I collagen, CTX-I
縮寫：

CTX-I
種屬：

Homo sapiens (Human)
樣本類型：

serum, plasma, tissue homogenates
檢測范圍：

0.625 ng/mL-40 ng/mL
靈敏度：

0.156 ng/mL
反應時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領域：

Others
測定原理：

quantitative
測定方法：

Sandwich

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of human CTX-I in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
	Sample	Serum(n=4)
1:1	Average %	88
	Range %	83-95
1:2	Average %	95
	Range %	91-98
1:4	Average %	97
	Range %	90-103
1:8	Average %	96
	Range %	91-101

回收率：

The recovery of human CTX-I spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

Sample Type	Average % Recovery	Range
Serum (n=5)	85	81-92
EDTA plasma (n=4)	96	93-106

標準曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

ng/ml	OD1	OD2	Average	Corrected
40	2.995	2.960	2.978	2.838
20	2.557	2.570	2.564	2.424
10	1.666	1.765	1.716	1.576
5	0.839	0.886	0.863	0.723
2.5	0.491	0.524	0.508	0.368
1.25	0.263	0.251	0.257	0.117
0.625	0.201	0.212	0.207	0.067
0	0.138	0.142	0.140

數據處理：

ELISA操作視頻及標曲繪制軟件下載
貨期：

3-5 working days

GPR37 Activation Alleviates Bone Cancer Pain via the Inhibition of Osteoclastogenesis and Neuronal Hyperexcitability K Wang, Y Zhang, R Shu, L Yuan, H Tu,Advanced Science,2025
C-terminal cross-linking telopeptide levels in COVID-19 patients: A prospective case-control study MA Gul,Advances in clinical and experimental medicine,2024
ERK-estrogen receptor α signaling plays a role in the process of bone marrow mesenchymal stem cell-derived exosomes protecting against ovariectomy-induced bone loss H Qi,Journal of orthopaedic surgery and research,2023
Effect of polyhydroxy-terminated PAMAM dendrimer on dentin matrix metalloproteinases within the hybrid layers Y Luo,BMC oral health,2023
Rosiglitazone Mitigates Dexamethasone-Induced Depression in Mice via Modulating Brain Glucose Metabolism and AMPK/mTOR Signaling Pathway A Alhaddad,Biomedicines,2023
Changes in bone turnover markers in patients without bone metastases receiving immune checkpoint inhibitors: An exploratory analysis F Pantano,Journal of bone oncology,2022
Praeruptorin B inhibits osteoclastogenesis by targeting GSTP1 and impacting on the S-glutathionylation of IKKβ K Xu,Biomedicine & pharmacotherapy,2022
TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling W Yang,Bone Research,2021
Umbilical cord N-terminal procollagen of type l collagen (P1NP) and beta C-terminal telopeptide (βCTX) levels in term pregnancies with vitamin D deficiency M Eraslan Sahin,Journal Gynecological Endocrinology,2020
Efficacy and Safety of Kudzu Flower–Mandarin Peel on Hot Flashes and Bone Markers in Women during the Menopausal Transition: A Randomized Controlled Trial JE Kim,Nutrients,2020
Association between bile acid metabolism and bone mineral density in postmenopausal women Zhao YX,Clinics (Sao Paulo),2020
The inhibitory effect of carboxyl-terminated polyamidoamine dendrimers on dentine host-derived matrix metalloproteinases in vitro in an etch-and-rinse adhesive system Wu Q, et al,Royal Society Open Science,2019
The Circadian Gene Clock Regulates Bone Formation Via PDIA3 Yuan G.et al,J Bone Miner Res. ,2016
Effect of Vitamin D on Peripheral Blood Mononuclear Cells from Patients with Psoriasis Vulgaris and Psoriatic Arthritis Cubillos S.et al,PLoS One.,2016
RANKL/Osteoprotegerin System and Bone Turnover in Hashimoto Thyroiditis. Konca Degertekin C.et al,Calcif Tissue Int.,2016
Combination Treatment with Whole Body Vibration and a Kidney-tonifying Herbal Fufang Prevent Osteoporosis in Ovariectomized Rats Wei QS et al,Orthop Surg,2015
Alteration of Cartilage Degeneration and Inflammation Markers in Temporomandibular Joint Osteoarthritis Occurs Proportionally Vos LM et al,J Oral Maxillofac Surg,2013

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Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.