Human C-type lectin domain family 18 member A(CLEC18A) ELISA kit

產(chǎn)品詳情

^{<rt id="t3cdq"></rt>}

文獻(xiàn)引用 (2) 說明書下載

Intra-assay Precision (Precision within an assay): CV%<8%

Three samples of known concentration were tested twenty times on one plate to assess.

Inter-assay Precision (Precision between assays): CV%<10%

Three samples of known concentration were tested in twenty assays to assess.

產(chǎn)品描述：

人C型凝集素結(jié)構(gòu)域家族18成員A(CLEC18A)酶聯(lián)免疫試劑盒（CSB-EL005521HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿、組織勻漿樣本中的CLEC18A含量。試劑盒檢測范圍為0.312 ng/mL-20 ng/mL，適用于基礎(chǔ)科研領(lǐng)域中對CLEC18A表達(dá)調(diào)控機(jī)制的研究，例如通過血清或血漿樣本評估其在系統(tǒng)免疫中的動態(tài)變化，或利用組織勻漿分析特定器官中該蛋白的分布特征。實驗操作兼容常規(guī)實驗室條件，可為免疫學(xué)、細(xì)胞信號通路及疾病模型研究提供可靠的數(shù)據(jù)支持，助力探索CLEC18A在生理病理過程中的分子作用。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
別名：

C-type lectin domain family 18 member A ELISA Kit; CL18A_HUMAN ELISA Kit; CLEC18A ELISA Kit; FLJ77955 ELISA Kit; Mannose receptor-like protein 2 ELISA Kit; MGC164804 ELISA Kit; Mrcl ELISA Kit; MRCL1 ELISA Kit; MRLP2 ELISA Kit
縮寫：

CLEC18A
Uniprot No.：

A5D8T8
種屬：

Homo sapiens (Human)
樣本類型：

serum, plasma, tissue homogenates
檢測范圍：

0.312 ng/mL-20 ng/mL
靈敏度：

0.078 ng/mL
反應(yīng)時間：

1-5h
樣本體積：

50-100ul
檢測波長：

450 nm
研究領(lǐng)域：

Others
測定原理：

quantitative
測定方法：

Sandwich

精密度：

線性度：

To assess the linearity of the assay, samples were spiked with high concentrations of human CLEC18A in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
	Sample	Serum(n=4)
1:1	Average %	92
	Range %	88-97
1:2	Average %	99
	Range %	95-107
1:4	Average %	89
	Range %	85-93
1:8	Average %	84
	Range %	80-88

回收率：

The recovery of human CLEC18A spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.

Sample Type	Average % Recovery	Range
Serum (n=5)	100	95-107
EDTA plasma (n=4)	90	85-94

標(biāo)準(zhǔn)曲線：

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

功能：

Binds polysaccharides in a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans.
基因功能參考文獻(xiàn)：
1. Plasma CLEC18 levels were correlated with the stage of HBV infection and could predict HBeAg loss and seroconversion in the patients with chronic hepatitis B (CHB) undergoing NUC therapy PMID: 30055605
亞細(xì)胞定位：

Secreted. Endoplasmic reticulum. Golgi apparatus. Endosome.
組織特異性：

Dectected in all cell lines tested and in peripheral blood cells.
數(shù)據(jù)庫鏈接：

HGNC: 30388

OMIM: 616571

KEGG: hsa:348174

STRING: 9606.ENSP00000288040

UniGene: Hs.592064