Human C-C motif chemokine 4(CCL4) ELISA kit
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中文名稱(chēng)：人CC趨化因子4(CCL4)酶聯(lián)免疫試劑盒
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貨號(hào)：CSB-EL004797HU
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規(guī)格：96T/48T
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價(jià)格：￥3600/￥2500
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促銷(xiāo)：
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其他：
產(chǎn)品詳情
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產(chǎn)品描述：人CC趨化因子4(CCL4)酶聯(lián)免疫試劑盒（CSB-EL004797HU）為雙抗夾心法ELISA試劑盒，定量檢測(cè)血清、血漿、組織勻漿樣本中的CCL4含量。CCL4是一種重要靶點(diǎn)。它屬于趨化因子，在免疫調(diào)節(jié)、炎癥反應(yīng)等生理過(guò)程中發(fā)揮關(guān)鍵作用。研究機(jī)制方面，CCL4與其受體結(jié)合，趨化特定免疫細(xì)胞遷移，在感染、自身免疫病等病理進(jìn)程中參與免疫應(yīng)答，是疾病治療和藥物研發(fā)的潛在方向。試劑盒檢測(cè)范圍為31.2 pg/ml- 2000 pg/ml，靈敏度為7.8 pg/ml。科研工作者可借助本產(chǎn)品定量分析CCL4在炎癥模型中的表達(dá)動(dòng)態(tài)，探究其在免疫細(xì)胞趨化、病原體感染后免疫應(yīng)答或腫瘤相關(guān)巨噬細(xì)胞活化中的作用機(jī)制，為免疫調(diào)控研究、疾病模型構(gòu)建及藥物干預(yù)效果評(píng)估提供可靠工具。本產(chǎn)品僅限科學(xué)研究使用，不適用于醫(yī)療診斷或其他非科研場(chǎng)景。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書(shū)。
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別名：MIP 1 beta ELISA Kit; Secreted protein G 26 ELISA Kit; ACT 2 ELISA Kit; ACT-2 ELISA Kit; ACT2 ELISA Kit; AT744.1 ELISA Kit; AT744.2 ELISA Kit; C C motif chemokine 4 ELISA Kit; C C motif chemokine 4 like ELISA Kit; C C motif chemokine ligand 4 like 1 ELISA Kit; C C motif chemokine ligand 4 like 2 ELISA Kit; CC chemokine ligand 4 ELISA Kit; CC chemokine ligand 4L1 ELISA Kit; CC chemokine ligand 4L1d2 ELISA Kit; CC chemokine ligand 4L2 ELISA Kit; CCL4 ELISA Kit; CCL4_HUMAN ELISA Kit; ccl4l 1 ELISA Kit; CCL4L ELISA Kit; CCL4L1 ELISA Kit; Chemokine (C C motif) ligand 4 ELISA Kit; Chemokine (C C motif) ligand 4 like 1 ELISA Kit; Chemokine (C C motif) ligand 4 like 1; telomeric ELISA Kit; Chemokine (C C motif) ligand 4 like 2 ELISA Kit; Chemokine CC Motif Ligand 4 ELISA Kit; G 26 ELISA Kit; G 26 T lymphocyte secreted protein ELISA Kit; G-26 T-lymphocyte-secreted protein ELISA Kit; HC21 ELISA Kit; Immune activation 2 ELISA Kit; LAG 1 ELISA Kit; LAG-1 ELISA Kit; LAG1 ELISA Kit; Lymphocyte activation gene 1 ELISA Kit; Lymphocyte activation gene 1 protein ELISA Kit; Macrophage inflammatory protein 1 beta ELISA Kit; Macrophage inflammatory protein 1-beta ELISA Kit; Macrophage inflammatory protein 1b2 ELISA Kit; MGC104418 ELISA Kit; MGC126025 ELISA Kit; MGC126026 ELISA Kit; MIP-1-beta ELISA Kit; MIP-1-beta(1-69) ELISA Kit; MIP-1-beta(3-69) ELISA Kit; MIP1 beta ELISA Kit; MIP1B ELISA Kit; MIP1B1 ELISA Kit; Monocyte adherence induced protein 5 alpha ELISA Kit; PAT 744 ELISA Kit; Protein H400 ELISA Kit; SCYA2 ELISA Kit; SCYA4 ELISA Kit; SCYA4L ELISA Kit; SCYA4L1 ELISA Kit; SCYA4L2 ELISA Kit; SCYQ4L2 ELISA Kit; Secreted protein G 26 ELISA Kit; Secreted protein G26 ELISA Kit; SIS gamma ELISA Kit; SIS-gamma ELISA Kit; Small inducible cytokine A4 (homologous to mouse Mip 1b) ELISA Kit; Small inducible cytokine A4 ELISA Kit; small inducible cytokine A4-like ELISA Kit; Small-inducible cytokine A4 ELISA Kit; T cell activation protein 2 ELISA Kit; T-cell activation protein 2 ELISA Kit
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縮寫(xiě)：
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Uniprot No.：
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種屬：Homo sapiens (Human)
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樣本類(lèi)型：serum, plasma, tissue homogenates
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檢測(cè)范圍：31.2 pg/ml - 2000 pg/ml
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靈敏度：7.8 pg/ml
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反應(yīng)時(shí)間：1-5h
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樣本體積：50-100ul
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檢測(cè)波長(zhǎng)：450 nm
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研究領(lǐng)域：Immunology
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測(cè)定原理：quantitative
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測(cè)定方法：Sandwich
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數(shù)據(jù)處理：
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貨期：3-5 working days
引用文獻(xiàn)
- High and selective cytotoxicity of ex vivo expanded allogeneic human natural killer cells from peripheral blood against bladder cancer: implications for natural killer cell instillation after transurethral resection of bladder tumor CL Yeh,Journal of experimental & clinical cancer research,2024
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相關(guān)產(chǎn)品
靶點(diǎn)詳情
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功能：Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
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基因功能參考文獻(xiàn)：
- identified 13 ADCC-activated genes. Six gene expression assays including 8 of the 13 genes (CCL3, CCL4/CCL4L1/CCL4L2, CD160, IFNG, NR4A3 and XCL1/XCL2) were analyzed in 127 kidney biopsies PMID: 25449536
- PCR results show that lower copy numbers of CCL4L1 are observed in the Caucasian population nd higher copy numbers are observed in the Black population of South Africa. PMID: 24727646
- CCL4L1 allele frequency is higher in severe psoriasis, whereas CCL4L2 is more frequent in patients with a milder disease. PMID: 21614014
- multiple copies of CCL3L1 and CCL4L1 present in a single diploid genome are the result of segmental duplication at chromosome 17q12 PMID: 15028295
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亞細(xì)胞定位：Secreted.
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蛋白家族：Intercrine beta (chemokine CC) family
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數(shù)據(jù)庫(kù)鏈接：
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