VPREB3 Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) VPREB3 Polyclonal antibody
Uniprot No.：

Q9UKI3
基因名：

VPREB3
別名：

N27C7 2 antibody; N27C7-2 antibody; Pre B lymphocyte protein 3 antibody; Pre-B lymphocyte protein 3 antibody; PRO619 antibody; Protein VPreB3 antibody; UNQ355 antibody; VPRE3_HUMAN antibody; VPREB3 antibody; VpreB3 protein antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Pre-B lymphocyte protein 3 protein (21-122AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells.
基因功能參考文獻：
1. A possible role for VPREB3 in aldosterone biosynthesis. PMID: 25861052
2. levels of VPREB3 mRNA in aldosterone-producing adenomas directly correlate to plasma aldosterone concentrations in peripheral blood of respective patients PMID: 25861052
3. mouse VpreB3 associates with mu heavy chains early in pre-B cell receptor biosynthesis PMID: 8491176
4. VpreB3 may play a role in the regulation of the maturation and secretion of free IgLC in chicken B cells PMID: 14670953
5. the combined immunohistochemical detection of VPREB3 and ID3 is applicable to the routine diagnostic in case of mature aggressive B-cell lymphomas. PMID: 24493312
6. Data show that the absence of VpreB3 is virtually always associated with wild-type c-MYC alleles. PMID: 20823132
7. the present study confirms the co-existence of surrogate lambda and kappa receptors that are proposed to work in concert to promote B lymphocyte maturation. PMID: 15757909
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蛋白家族：

Immunoglobulin superfamily
組織特異性：

Expressed in B-cell precursors. Expressed in fetal liver, bone marrow, spleen and lymph node.
數據庫鏈接：

HGNC: 12710

OMIM: 605017

KEGG: hsa:29802

STRING: 9606.ENSP00000248948

UniGene: Hs.136713

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