UBXN2B Antibody, Biotin conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) UBXN2B Polyclonal antibody
Uniprot No.：

Q14CS0
基因名：

UBXN2B
別名：

NSFL1 cofactor p37 antibody; p37 antibody; p97 cofactor p37 antibody; UBX domain containing protein 2B antibody; UBX domain protein 2B antibody; UBX domain-containing protein 2B antibody; UBX2B_HUMAN antibody; UBXN2B antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human UBX domain-containing protein 2B protein (2-250AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

Biotin
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis.
基因功能參考文獻：
1. these results demonstrate that p37 phosphorylation on Serine-56 and Threonine-59 is important for Golgi disassembly at mitosis. PMID: 20875789
亞細胞定位：

Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum. Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
蛋白家族：

NSFL1C family
數據庫鏈接：

HGNC: 27035

OMIM: 610686

KEGG: hsa:137886

STRING: 9606.ENSP00000382507

UniGene: Hs.155572

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