LPO Antibody, FITC conjugated
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中文名稱：LPO兔多克隆抗體, FITC偶聯(lián)
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貨號：CSB-PA013066LC01HU
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規(guī)格：￥880
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) LPO Polyclonal antibody
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Uniprot No.：
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基因名：LPO
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別名：LPO antibody; SAPX antibody; Lactoperoxidase antibody; LPO antibody; EC 1.11.1.7 antibody; Salivary peroxidase antibody; SPO antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human Lactoperoxidase protein (81-190AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：FITC
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
產(chǎn)品提供形式：Liquid
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
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靶點詳情
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功能：Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN). May contribute to airway host defense against infection.
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基因功能參考文獻：
- The crystal structure of the complex of LPO with MZY showed that MZY bound to LPO in the substrate-binding site on the distal heme side. MZY was oriented in the substrate-binding site in such a way that the sulfur atom is at a distance of 2.58 A from the heme iron PMID: 28653416
- LPO mRNA was undetectable in the gastric mucosa. PMID: 27048452
- Oral peroxidase activity as a marker of chronic alcohol abuse may help in the diagnosis of alcoholism. PMID: 23042278
- establish urate as a likely physiological substrate for LPO that will influence host defense and give rise to reactive electrophilic metabolites PMID: 24928513
- High intensity of caries is associated with increased levels of some salivary components - sIgA, histatin-5 and lactoperoxidase. PMID: 24974109
- a functional LPO system exists in human airways and may contribute to airway host defense against infection PMID: 12626341
- lactoperoxidase may play an important role in the metabolic events associated with Parkinson's disease PMID: 15384204
- Analysis of the role of thiocyanate (SCN-), in modulating the catalytic activity of myeloperoxidase (MPO) and other members of the lactoperoxidase (LPO) and eosinophil peroxidase (EPO) PMID: 15894800
- Splice variants may contribute to LPO molecular heterogeneity and its regulation by intracellular compartmental localization in respiratory epithelium. PMID: 19059195
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亞細胞定位：Secreted.
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蛋白家族：Peroxidase family, XPO subfamily
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組織特異性：Mammary gland; milk and salivary gland. Found in bronchial submucosal glands.
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