ITGB1BP2 Antibody, HRP conjugated

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) ITGB1BP2 Polyclonal antibody
Uniprot No.：

Q9UKP3
基因名：

ITGB1BP2
別名：

ITGB1BP2 antibody; MSTP015 antibody; Integrin beta-1-binding protein 2 antibody; Melusin antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Recombinant Human Integrin beta-1-binding protein 2 protein (130-329AA)
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

HRP
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA
Protocols：

ELISA Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

May play a role during maturation and/or organization of muscles cells.
基因功能參考文獻(xiàn)：
1. Studies in mouse show that melusin prevents cardiac dilation during chronic pressure overload by specifically sensing mechanical stress. PMID: 12496958
2. Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy PMID: 23124043
3. The altered melusin pathways and CDC42 parallel the cardiac function progression during cardiac remodeling post-MI. PMID: 21546274
4. Our analysis revealed an extremely low number of variations in the ITGB1BP2 gene in nearly 1000 hypertensive/cardiopathic and healthy individuals, thus suggesting a high degree of conservation of the melusin gene within the populations analyzed PMID: 20017903
組織特異性：

Expressed in skeletal and cardiac muscles but not in other tissues.
數(shù)據(jù)庫鏈接：

HGNC: 6154

OMIM: 300332

KEGG: hsa:26548

STRING: 9606.ENSP00000362935

UniGene: Hs.109999

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